Sitagliptin N-Boc IMpurity Chemical Properties

Melting point:

188-191 °C(Solv: toluene (108-88-3))

Density 

1.46±0.1 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

Chloroform (Slightly, Heated), DMSO (Slightly), Ethyl Acetate (Slightly)

pka

11.60±0.46(Predicted)

form 

Solid

color 

White

Sitagliptin N-Boc IMpurity Usage And Synthesis

Uses

N-Boc-Sitagliptin is the N-Boc protected derivative of Sitagliptin (S490990), a dipeptidyl peptidase-4 inhibitor that is used for glycemic control for patients with type 2 diabetes.

Sitagliptin N-Boc IMpurity(486460-23-5)Related Product Information

• 1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)-
• Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate
• Sitagliptin Impurity 28
• Sitagliptin phosphate monohydrate
• Sitagliptin N-Phoshate IMpurity
• Sitagliptin Impurity 27
• Sitagliptin
• Sitagliptin
• Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate
• (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
• Sitagliptin Impurity 14
• (R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid
• 2,4,5-Trifluorobenzaldehyde
• BOC-(S)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID
• Sitagliptin Impurity 35
• Sitagliptin impurity H HCl
• Sitagliptin Impurity 31
• Sitagliptin N-Sulfate