TMA-DPH Chemical Properties

Melting point:

237 °C (dec.)(lit.)

storage temp. 

−20°C

solubility 

DMF: soluble

form 

A crystalline solid

color 

Off-white to light brown

Appearance

Solid Powder

Safety Information

Hazard Codes 

T

Risk Statements 

61

Safety Statements 

53-45

WGK Germany 

3

F 

8

TMA-DPH Usage And Synthesis

Description

TMA-DPH is a hydrophobic fluorescent membrane probe used to measure membrane fluidity. It anchors to the cell surface and localizes in different regions of the phospholipid bilayer. By analyzing its fluorescence polarization values in the plasma membrane and its substructures, researchers can determine cell membrane fluidity.
TMA-DPH is particularly well-suited for studying monolayer dynamics in lipoproteins and similar systems. It can also be employed in fluorescent labeling experiments due to the following advantages:
High sensitivity: TMA-DPH exhibits excellent stability and sensitivity in lipid environments, effectively reflecting changes in membrane potential and fluidity.
Rapid integration: Upon contact with cells, TMA-DPH quickly incorporates into the cell membrane, enabling real-time detection.
Dynamic tracking: In in vitro studies, TMA-DPH can monitor dynamic membrane changes, including lateral diffusion, rotation, and side-to-side fluctuations.

Uses

Fluorescent Probe for membrane fluidity

Uses

N,N,N-Trimethyl-4-(6-phenyl-1,3,5-hexatrien-1-yl)phenylammonium p-Toluenesulfonate is a fluorescent reporter probe used to measure the fluidity of membranes and liposomes

Biological Activity

Lipid marker for endocytosis.

Excitation / Emission Maximum

355 nm/430 nm

TMA-DPH(115534-33-3)Related Product Information

• DIO
• FM4-64
• 4-Nitrophenylphosphorylcholine
• 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE
• TMA-DPH
• 1-(4-TRIMETHYLAMMONIUMPHENYL)-6-PHENYL-1, 3,5-HEXATRIENE P-TOLUENESULFONATE (TMA-DPH)
• PHENYLTRIMETHYLAMMONIUM HYDROXIDE
• 1,6-DIPHENYL-1,3,5-HEXATRIENE
• TETRAMETHYLAMMONIUM P-TOLUENESULFONATE
• 1-[4-(DIMETHYLAMINO)PHENYL]-6-PHENYLHEXATRIENE