Basic information Safety Supplier Related

Thiol-PEG3-phosphonic acid ethyl ester

Basic information Safety Supplier Related

Thiol-PEG3-phosphonic acid ethyl ester Basic information

Product Name:
Thiol-PEG3-phosphonic acid ethyl ester
Synonyms:
  • Thiol-PEG3-phosphonic acid ethyl ester
  • 2-[2-[2-(2-diethoxyphosphorylethoxy)ethoxy]ethoxy]ethanethiol
  • Diethyl-(2-(2-[2-(2-mercapto-ethoxy)-ethoxy]-ethoxy)-ethyl)phosphonate
  • Phosphonic acid, P-[2-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]ethyl]-, diethyl ester
CAS:
1360716-43-3
MF:
C12H27O6PS
MW:
330.38
Mol File:
1360716-43-3.mol
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Thiol-PEG3-phosphonic acid ethyl ester Chemical Properties

Boiling point:
421.9±40.0 °C(Predicted)
Density 
1.113±0.06 g/cm3(Predicted)
pka
9?+-.0.10(Predicted)
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Thiol-PEG3-phosphonic acid ethyl ester Usage And Synthesis

Uses

Thiol-PEG3-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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