TAT-cyclo-CLLFVY Chemical Properties

Density 

1.51±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

form 

Solid

color 

White to off-white

Water Solubility 

Soluble to 1 mg/ml in water

Sequence

Cys-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-Gln.cyclo(Cys-Leu-Leu-Phe-Val-Tyr) (Disulfide bridge:Cys1-Cys1')

TAT-cyclo-CLLFVY Usage And Synthesis

Uses

TAT-cyclo-CLLFVY is a selective HIF-1 dimerization inhibitor. It blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β.

storage

Store at -20°C

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