Methyltetrazine-propylamine HCl salt
Methyltetrazine-propylamine HCl salt Basic information
- Product Name:
- Methyltetrazine-propylamine HCl salt
- Synonyms:
-
- Methyltetrazine-propylamine HCl salt
- 1-Propanamine, 3-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-
- 3-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]propan-1-amine
- CAS:
- 1802978-47-7
- MF:
- C12H15N5O
- MW:
- 245.28
- Mol File:
- 1802978-47-7.mol
More
Less
Methyltetrazine-propylamine HCl salt Chemical Properties
- Boiling point:
- 474.6±55.0 °C(Predicted)
- Density
- 1.198±0.06 g/cm3(Predicted)
- pka
- 9.24±0.10(Predicted)
More
Less
Methyltetrazine-propylamine HCl salt Usage And Synthesis
Description
Methyltetrazine-Propylamine is click chemistry reagent, the amine group can be attached with carboxylic acid containing molecule in the presence of reagnet such as EDC or HATU. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene)
Uses
Methyltetrazine-propylamine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
Alkyl-Chain
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Methyltetrazine-propylamine HCl saltSupplier
Shanghai Send Pharmaceutical Technology Co., Ltd.
- Tel
- 021-58088081 Q2635253576
- hailey@shsendpharm.com
Alfa Chemistry
- Tel
- +1-5166625404;
- Info@alfa-chemistry.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
- Tel
- 13892832556
- 2440688701@qq.com
Nanjing Shizhou Biology Technology Co.,Ltd
- Tel
- 025-85563444 18351873721
- purchase@synzest.com