H-GAMMA-GLU-TYR-OH Chemical Properties

Melting point:

219-221 °C

Boiling point:

690.4±55.0 °C(Predicted)

Density 

1.414±0.06 g/cm3(Predicted)

storage temp. 

-15°C

form 

Solid

pka

2.22±0.10(Predicted)

color 

White to off-white

Sequence

{γ-Glu}-Tyr

H-GAMMA-GLU-TYR-OH Usage And Synthesis

Uses

γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC50=6.77 mM), is a potentially functional component of the type 2 diabetes diet[1].

Definition

ChEBI: Gamma-Glu-Tyr is a dipeptide composed of L-glutamic acid and L-tyrosine joined by a peptide linkage. It has a role as a human metabolite. It is a dipeptide, a secondary carboxamide, a dicarboxylic acid, a primary amino compound and a member of phenols. It is functionally related to a L-glutamic acid and a L-tyrosine. It is a conjugate acid of a gamma-Glu-Tyr(1-).

IC 50

DPP-4: 6.77 mM (IC₅₀)

References

[1] Yang J, et al. γ‐Glu‐Met synthesised using a bacterial glutaminase as a potential inhibitor of dipeptidyl peptidase IV[J]. International Journal of Food Science & Technology, 2018, 53(5): 1166-1175.

H-GAMMA-GLU-TYR-OH(7432-23-7)Related Product Information

• DL-Glutamine
• H-GAMMA-GLU-GLY-OH
• N-(2-Hydroxyethyl)-1,4-butanediamine
• L-Glutamine
• L-Ornithine
• L-Theanine
• H-GAMMA-GLU-PHE-OH
• H-GAMMA-GLU-ALA-OH
• L-Theanine
• 2-amino-4-(propan-2-ylcarbamoyl)butanoic acid
• H-GAMMA-GLU-ABU-OH
• L-Ornithine acetate
• H-GAMMA-GLU-TYR-OH