L-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE Chemical Properties

Melting point:

254 °C (dec.)(lit.)

solubility 

H₂O: 100 mg/mL

CAS DataBase Reference

7048-02-4(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

MS3119000

F 

10

MSDS

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L-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE Usage And Synthesis

Uses

L-Histidine Hydrochloride Monohydrate can be used as AhR activators to treat gluten-induced gastrointestinal diseases. It can also be used for hair coloring method.

Purification Methods

Crystallise the monohydrochloride from aqueous EtOH or 60% aqueous EtOH (m 259odec). Alternatively dissolve 10g in 50mL of H2O, decolourise with Norite, filter, evaporate it in a vacuum to a syrup, cool to room temperature, add 95% EtOH with stirring until slightly turbid, scratch the sides of the vessel until crystals form, then add slowly 40mL of EtOH and keep at 0o overnight, filter the solid off, wash it several times with EtOH and dry it in a vacuum. [Cox J Biol Chem 78 475 1929, Cox et al. J Biol Chem 81 73 1929, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 1972, 2098 1961, Beilstein 25 II 407, 25 III/IV 4346.]

L-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE(7048-02-4)Related Product Information

• L-Phenylalanine
• DL-HISTIDINE MONOHYDROCHLORIDE
• L-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE,(S)-(+)-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE
• D-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE
• DL-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE