Basic information Uses Application Safety Supplier Related

(S)-(-)-2-AMINO-1,1-DIPHENYL-1-PROPANOL

Basic information Uses Application Safety Supplier Related

(S)-(-)-2-AMINO-1,1-DIPHENYL-1-PROPANOL Basic information

Product Name:
(S)-(-)-2-AMINO-1,1-DIPHENYL-1-PROPANOL
Synonyms:
  • (S)-(-)-2-AMINO-1,1-DIPHENYL-1-PROPANOL
  • Droxidopa Impurity 18
  • 2-amino-1,2-diphenyl-1-propanol
  • (S)-2-AMINO-1,1-DIPHENYL-1-PROPANOL
  • (S)-2-AMINO-1,2-DIPHENYL-1-PROPANOL
  • (2S)-2-amino-1,1-diphenylpropan-1-ol
  • 1,1-DIPHENYL-L-ALANINOL
  • (-)-[(S)-1-Aminoethyl]diphenylmethanol
CAS:
78603-91-5
MF:
C15H17NO
MW:
227.3
EINECS:
622-109-8
Product Categories:
  • chiral
Mol File:
78603-91-5.mol
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(S)-(-)-2-AMINO-1,1-DIPHENYL-1-PROPANOL Chemical Properties

Melting point:
100-102 °C(lit.)
alpha 
-90 º (C=1 IN CHLOROFORM)
Boiling point:
407.8±40.0 °C(Predicted)
Density 
1.112±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
solid
pka
11.25±0.50(Predicted)
color 
Yellow
optical activity
[α]20/D 90°, c = 1 in chloroform
BRN 
3052863
InChI
InChI=1/C15H17NO/c1-12(16)15(17,13-8-4-2-5-9-13)14-10-6-3-7-11-14/h2-12,17H,16H2,1H3/t12-/s3
InChIKey
FMBMNSFOFOAIMZ-PLAQIDKDNA-N
SMILES
C(O)([C@@H](N)C)(C1C=CC=CC=1)C1C=CC=CC=1 |&1:2,r|
CAS DataBase Reference
78603-91-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
9
HS Code 
2922190090

MSDS

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(S)-(-)-2-AMINO-1,1-DIPHENYL-1-PROPANOL Usage And Synthesis

Uses

(S)-2-amino-1,1-diphenyl-1-propanol is an alcohol derivative that can be used as an intermediate in organic synthesis.

Application

In asymmetric synthesis, the synthesis of chiral catalysts or chiral auxiliaries is crucial. Chiral amino alcohols are widely used as ligands or catalysts for catalyzing asymmetric synthetic reactions and are also important precursors for the synthesis of many chiral drugs, natural products, and chemical and biological functional materials. (S)-2-amino-1,1-diphenyl-1-propanol belongs to the optically active β-amino alcohols. It can be used for asymmetric reduction of pre-chiral ketones, asymmetric catalytic epoxidation reactions, and asymmetric catalytic alkylation reactions of carbonyl compounds. (S)-2-amino-1,1-diphenyl-1-propanol has also been reported as an intermediate in the synthesis of chiral complexes in asymmetric cyclopropanation reactions.

Chemical Properties

white to light yellow crystal powde

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