L-Alaninol Chemical Properties

Melting point:

-2°C

Boiling point:

72-73 °C11 mm Hg(lit.)

alpha 

21.8 º (c=2,ethanol)

Density 

0.965 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.450

Flash point:

145 °F

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

Water Solubility 

Completely miscible in water

solubility 

Chloroform, Methanol (Slightly)

pka

12.88±0.10(Predicted)

form 

Oily Liquid

color 

Clear colorless to yellow

Specific Gravity

0.96

optical activity

[α]20/D +18°, neat

Sensitive 

Hygroscopic

BRN 

1718865

CAS DataBase Reference

2749-11-3(CAS DataBase Reference)

NIST Chemistry Reference

1-Propanol, 2-amino-, (S)-(2749-11-3)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

34-36/37/38

Safety Statements 

26-36/37/39-45-36

RIDADR 

UN 2735 8/PG 2

WGK Germany 

3

F 

10-23

HazardClass 

8

PackingGroup 

III

HS Code 

29221990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

L-Alaninol Usage And Synthesis

Chemical Properties

Colorless liquid

Uses

S-(+)-2-Amino-1-propanol is an aliphatic amino alcohol shown to induce an antiproliferative effect in B16 melanoma cells. S-(+)-2-Amino-1-propanol is used in the preparation of oxazolines which are of ten used as ligands in homogeneous catalysis.

Uses

(S)-(+)-2-Amino-1-propanol (L-Alaninol) may be used in the preparation of unsymmetrical tridentate Schiff base ligands via condensation with carbonyl compounds. It may also be used as a chiral auxillary for the preparation of tert-butyl 4-N-[(2-hydroxy-1-(S)-methyl)ethylamino]-2-methylene-4-(S)-phenyl-butyrate.

Definition

ChEBI: An amino alcohol that is L-alanine in which the carboxy group has been reduced to the corresponding alcohol.

Biochem/physiol Actions

Pseudomonas sp. strain KIE171 was able to grow with L-alaninol [S-(+)-2-amino-1-propanol] as the sole carbon source[1]. W?sch et al. found that mutant KIE171-BI transformed isopropylamine to L-alaninol, mutant KIE171-BII failed to do so.

Purification Methods

Purify it as for S-2-amino-3-methylbutan-1-ol below. [Beilstein 4 IV 1615.]

References

[1] Susana I de Azevedo W?sch. “Transformation of isopropylamine to L-alaninol by Pseudomonas sp. strain KIE171 involves N-glutamylated intermediates.”Applied and Environmental Microbiology (2002): 68.

L-Alaninol(2749-11-3)Related Product Information

• ALTRENOGEST
• Glycine
• 2-Amino-2-methyl-1-propanol
• Betaine
• EC 2.6.1.2
• 1-Propanol
• Glucosamine
• Acetaminophen
• Sulfamic acid
• Aminopyrine
• Isopropyl alcohol
• 3-Dimethylamino-1-propanol
• (S)-2-AMINO-PROPAN-1-OL,DL-2-Amino-1-propanol;DL-Alaninol; DL-Alaninol ,DL-ALANINOL FREE BASE
• Ethyl N-benzoyl-L-tyrosinate
• Ethyl N-acetyl-L-tyrosinate hydrate
• 3-Aminopropanol
• TRANS-2-AMINOCYCLOHEXANOL HYDROCHLORIDE
• (±)-1-amino-propan-2-o