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Amino-2-propanol

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Amino-2-propanol Basic information

Product Name:
Amino-2-propanol
Synonyms:
  • MONOISOPROPANOLAMINE
  • MIPA
  • THREAMINE
  • RARECHEM AL BW 2385
  • (+/-)-1-AMINO-2-PROPANOL
  • 1-AMINO-2-PROPANOL
  • 1-AMINOISOPROPANOL
  • 1-AMINOISOPROPYL ALCOHOL
CAS:
78-96-6
MF:
C3H9NO
MW:
75.11
EINECS:
201-162-7
Mol File:
78-96-6.mol
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Amino-2-propanol Chemical Properties

Melting point:
-2 °C (lit.)
Boiling point:
160 °C (lit.)
Density 
0.973 g/mL at 25 °C (lit.)
vapor density 
2.6 (vs air)
vapor pressure 
<1 mm Hg ( 20 °C)
refractive index 
n20/D 1.4478(lit.)
FEMA 
3965 | 1-AMINO-2-PROPANOL
Flash point:
165 °F
storage temp. 
2-8°C
pka
12.92±0.35(Predicted)
form 
Liquid
color 
Clear
Odor
slt ammonia odor
PH
11.3 (10g/l, H2O, 20℃)
explosive limit
1.9-10.4%(V)
Water Solubility 
freely soluble
FreezingPoint 
1.4℃
Sensitive 
Hygroscopic
JECFA Number
1591
BRN 
605275
Stability:
Stable. Substances to be avoided include strong oxidizing agents. Combustible. Hygroscopic.
InChIKey
HXKKHQJGJAFBHI-UHFFFAOYSA-N
CAS DataBase Reference
78-96-6(CAS DataBase Reference)
NIST Chemistry Reference
2-Propanol, 1-amino-(78-96-6)
EPA Substance Registry System
Monoisopropanolamine (78-96-6)
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Safety Information

Hazard Codes 
C,Xn
Risk Statements 
34-21/22
Safety Statements 
23-26-36-45-36/37
RIDADR 
UN 2735 8/PG 2
WGK Germany 
1
RTECS 
UA5775000
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29221980
Hazardous Substances Data
78-96-6(Hazardous Substances Data)
Toxicity
LD50 orl-rat: 1715 mg/kg GTPZAB 30(7),46,86

MSDS

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Amino-2-propanol Usage And Synthesis

Chemical Properties

colourless liquid

Chemical Properties

1-Amino-2-propanol has a fishy odor.

Occurrence

Reportedly present in sherry.

Uses

Synthetic and semisynthetic machine lubricating/cutting oil formulations have included isopropanolamine, diisopropanolamine, and triethanolamine, together with nitrites; consequently the EPA has promulgated standards regarding the composition of cutting fluids. No additional uses were found in the literature.

Uses

Amino-2-propanol is used to study the effect of temperature and water content on the molecular structure and hydrogen bonding of amino-2-propanol, which has been examined by Fourier transform near-infrared (FT-NIR) spectroscopy. Also used in used in the synthesis of protein kinase CK2 inhibitors used in the treatment of neoplasia and other infective diseases.

Definition

ChEBI: Any amino alcohol that is propan-2-ol substituted by an amino group at position 1.

Preparation

By employing Salmonella, mutatant cobD, and aminopropanol

Aroma threshold values

Detection at 28 ppm in water

General Description

A colorless liquid with a slight ammonia-like odor. Less dense than water and soluble in water. Flash point 165°F. Corrosive to metals and tissue. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. Used in plastics, paints, cutting oils, and specialized cleaning compounds.

Air & Water Reactions

Water soluble.

Reactivity Profile

Amino-2-propanol is an aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard

Vapor irritates eyes and nose. Liquid causes local injury to mouth, throat, digestive tract, skin, and eyes.

Fire Hazard

Special Hazards of Combustion Products: Irritating vapors generated when heated.

Safety Profile

Poison by intraperitoneal route.Moderately toxic by ingestion and skin contact. A skin andsevere eye irritant. Moderately flammable in presence ofheat, flame, sparks, powerful oxidizers. Ignites on contactwith cellulose nitrate of high surface area. C

Amino-2-propanolSupplier

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