2',6'-DIHYDROXY-4'-METHOXYCHALCONE Chemical Properties

Melting point:

145°C

Boiling point:

521.1±50.0 °C(Predicted)

Density 

1.282±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO: Soluble: =10 mg/ml
Ethanol: Soluble: =10 mg/ml

form 

Solid

pka

6.70±0.40(Predicted)

color 

Light yellow to orange

2',6'-DIHYDROXY-4'-METHOXYCHALCONE Usage And Synthesis

Uses

Pinostrobin Chalcone is an estrogenic compound from the plant leaves of Carya cathayensis Sarg.

Definition

ChEBI: Pinostrobin chalcone is a member of chalcones.

References

[1] BARAA M. I. S. JADALLA. In Vitro Alpha-Glucosidase and Alpha-Amylase Inhibitory Activities and Antioxidant Capacity of Helichrysum cymosum and Helichrysum pandurifolium Schrank Constituents[J]. Separations, 2022. DOI: 10.3390/separations9080190
[2] E C TORRES-SANTOS. Selective effect of 2’,6’-dihydroxy-4’-methoxychalcone isolated from Piper aduncum on Leishmania amazonensis.[J]. Antimicrobial Agents and Chemotherapy, 1999, 43 5: 1234-1241. DOI: 10.1128/aac.43.5.1234
[3] SRI NURESTRI ABDUL MALEK. Phytochemical and cytotoxic investigations of Alpinia mutica rhizomes.[J]. Molecules, 2011, 16 1: 583-589. DOI: 10.3390/molecules16010583
[4] NEERAJ K. PATEL  Kamlesh K B. Pinostrobin and Cajanus lactone isolated from Cajanus cajan (L.) leaves inhibits TNF-α and IL-1β production: In vitro and in vivo experimentation[J]. Phytomedicine, 2014, 21 7: Pages 946-953. DOI: 10.1016/j.phymed.2014.02.011

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