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Hesperidin methylchalcone

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Hesperidin methylchalcone Basic information

Product Name:
Hesperidin methylchalcone
Synonyms:
  • (e)-osyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)
  • 2’,3,4’-trihydroxy-4,6’-dimethoxy-chalcon4’-(6-o-(6-deoxy-alpha-l-mannopyr
  • 2-propen-1-one,1-[4-[[6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyran
  • anosyl)-beta-d-glucopyranoside)
  • Hesperidine Methyl Chalcone
  • 1-[4-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one
  • (E)-3-(3-HYDROXY-4-METHOXY-PHENYL)-1-[2-HYDROXY-6-METHOXY-4-[(2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-((2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXYMETHYL)-TETRAHYDRO-PYRAN-2-YLOXY]-PHENYL]-PROPENONE
  • HESPERIDIN METHYL CHALCONE
CAS:
24292-52-2
MF:
C29H36O15
MW:
624.59
EINECS:
246-128-2
Product Categories:
  • CITRIMORE
  • Chalcones
  • C15 to C38
  • Carbonyl Compounds
  • Ketones
Mol File:
24292-52-2.mol
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Hesperidin methylchalcone Chemical Properties

Melting point:
120 °C (dec.)(lit.)
alpha 
-71 º (c=1 in ethanol)
Boiling point:
583.81°C (rough estimate)
Density 
1.3090 (rough estimate)
refractive index 
1.5940 (estimate)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
6.71±0.40(Predicted)
form 
Solid
color 
Yellow
optical activity
[α]20/D 71°, c = 1 in ethanol
InChIKey
FDHNLHLOJLLXDH-JIYHLSBYSA-N
LogP
0.267 (est)
CAS DataBase Reference
24292-52-2(CAS DataBase Reference)
EPA Substance Registry System
Hesperidin methylchalcone (24292-52-2)
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Safety Information

WGK Germany 
3
RTECS 
FL7085000

MSDS

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Hesperidin methylchalcone Usage And Synthesis

Description

Hesperidin methylchalcone (HMC) is a flavonoid with potent free radical quenching properties and is a highly complex compound typically found in bright-colored plants and flowers. In skincare, it is primarily used as an antioxidant, with noted effects on circulation for reducing dark circles and melanin synthesis. Hesperidin, in its raw form, has poor absorption. Hence, it is modified into HMC for better stability and skin compatibility.

Uses

hesperidin methyl chalcone is a citrus bioflavonoid. extracted from the peel of sweet oranges, it has anti-oxidant properties. It is used in eye care preparations for reducing the appearance of dark circles.

Uses

Hesperidin Methylchalcone is a flavonoid agent used in the treatment of venous insufficiency.

benefits

Hesperidin MethylChalcone (HMC) is a very interesting antioxidant as it is one of the rare Barrier Repair Antioxidants. It is able to increase Filaggrin and B-glucocerebrosidase which are essential for Ceramide production. The other notable use for HMC is its ability to reduce capillary permeability for dark cicles around the eyes.
The benefits of HMC include: Anti-dark Circles, Antioxidant, Barrier Repair, and Anti-aging.

Hesperidin methylchalconeSupplier

Sichuan Benepure Pharmaceutical Co., Ltd. Gold
Tel
028-028-86798880 13308041363
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online@benepure.com
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Email
zhangsn@titansci.com
XiaoGan ShenYuan ChemPharm co,ltd
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0712-0712-2580635 15527768850
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1791901229@qq.com
China Langchem Inc.
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0086-21-58956006
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
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