4-(METHYLSULFONYL)PHENYLBORONIC ACID Chemical Properties

Melting point:

275-277 °C

Boiling point:

445.5±51.0 °C(Predicted)

Density 

1.39±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

soluble in Methanol

pka

7.22±0.10(Predicted)

form 

Powder

color 

Off-white

CAS DataBase Reference

149104-88-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

37/39-26-24/25-22

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29163990

MSDS

• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-(METHYLSULFONYL)PHENYLBORONIC ACID Usage And Synthesis

Chemical Properties

Off-white powder

Uses

4-(Methylsulfonyl)phenylboronic Acid is a heteroaryl boronic acid that was tested for their in vitro hormone-sensitive lipase inhibitory properties.

Uses

4-(Methanesulfonyl)phenylboronic acid may be used as reagent for:

• sequential Suzuki cross-coupling reactions
• Copper-catalyzed oxidative trifluoromethylthiolation of aryl boronic acids
• directed metalation and regioselective functionalization of 3-bromofuran and related heterocycles
• Barton-Zard pyrrole cyclocondensations and Baeyer-Villiger oxidations
• diplar cycloaddition and palladium-catalyzed cross-coupling processes
• continuous flow Suzuki reactions for odanacatib intermediate synthesis

• diarylaminopyridines as potential anti-malarial agents
• hydropyranopyrazine via chloropyrazinecarboxaldehyde and olefination
• biaryl sulfone derivatives as antagonists of the histamine H3 receptor
• novel kinase inhibitor scaffolds with potential antitumor effects
• Hepatitis C virus inhibition activity of N-hydroxyisoquinoline di

General Description

Contains varying amounts of anhydride

4-(METHYLSULFONYL)PHENYLBORONIC ACID(149104-88-1)Related Product Information

• 4-Morpholinecarbonyl chloride
• 4-tert-Butylbenzenesulfonyl chloride
• 4-Methyl-1,3-thiazole-2-carboxylic acid
• 4-Methylpyridine-3-boronic acid
• 4-PyridazineMethanaMine hydrochloride
• Tosylmethyl isocyanide
• 4-(METHANESULFINYL)BENZENEBORONIC ACID
• 2-CHLORO-4-METHYLSULFONYLPHENYLBORONIC ACID
• 2-(METHYLSULFONYL)PHENYLBORONIC ACID
• 3-(METHYLSULFONYL)PHENYLBORONIC ACID,3-(methylsulfonyloxy)phenylboronic acid
• 4-(Methanesulfonyl)phenylboronic acid pinacol ester
• 4-(ETHYLSULFONYL)PHENYLBORONIC ACID
• 4-(METHYLSULFONYL)PHENYLBORONIC ACID
• 4-(ISOPROPYLSULFONYLPHENYL)BORONIC ACID
• 3-Fluoro-4-(methylsulfonyl)phenylboronic acid
• 3-FLUORO-4-(METHYLSULFONYL)PHENYLBORONIC ACID
• 2-Fluoro-4-methylsulfonylphenylboronic acid
• 2-FLUORO-4-(METHYLSULFONYL)PHENYLBORONIC ACID