6-(METHYLAMINO)PURINE RIBOSIDE
6-(METHYLAMINO)PURINE RIBOSIDE Basic information
- Product Name:
- 6-(METHYLAMINO)PURINE RIBOSIDE
- Synonyms:
-
- N6-METHYLADENOSINE
- 6-(METHYLAMINO)PURIN
- 6-(METHYLAMINO)PURINE RIBOSIDE
- MF:
- C11H15N5O4
- MW:
- 281.27
- Mol File:
- Mol File
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6-(METHYLAMINO)PURINE RIBOSIDE Chemical Properties
- Melting point:
- >147°C (dec.)
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly, Heated)
- form
- Solid
- color
- White to Off-White
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6-(METHYLAMINO)PURINE RIBOSIDE Usage And Synthesis
Uses
N6-Methyladenosine is the most common internal modification of eukaryotic mRNA. The result of this modification is specifically recognized mRNA in the cytoplasm which regulates mRNA stability.N6-Methyladenosine is made when a protein complex containin the writer enzyme METTL3 adds a methyl group to adenosine. Two different eraser enzymes ALKBH5 and FTO can remove a methyl group to turn m6A bach into adenosine.