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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Amino Acids and Derivatives >  Proline derivatives >  (R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER

(R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER

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(R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Basic information

Product Name:
(R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER
Synonyms:
  • (R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER
  • BOC-D-PRO(4-OXO)
  • N-BOC-4-OXO-D-PROLINE
  • N-Boc-4-oxo-D-proline Methyl ester
  • 1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1-(1,1-diMethylethyl) ester, (2R)-
  • (R)-1-(tert-Butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid
  • (2R)-N-Boc-4-oxo-proline
  • (2R)-1-[(tert-butoxy)carbonyl]-4-oxopyrrolidine-2-carboxylic acid
CAS:
364077-84-9
MF:
C10H15NO5
MW:
229.23
Product Categories:
  • pharmacetical
Mol File:
364077-84-9.mol
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(R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Chemical Properties

Boiling point:
390.8±42.0 °C(Predicted)
Density 
1.304±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
3.85±0.20(Predicted)
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(R)-4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Usage And Synthesis

Uses

(2R)-N-Boc-4-oxo-proline was used as a reactant in the preparation of 4,4-disubstituted pyrrolidine-1,2-dicarboxamides which are potent factor Xa inhibitors with increased human half life. Also used in the synthesis of azacyclic FTY720 analogues which show potential for use in strategy to kill cancer cells as they restrict access to extracellular nutrients.

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