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N-Boc-3-pyrrolidinone

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N-Boc-3-pyrrolidinone Basic information

Product Name:
N-Boc-3-pyrrolidinone
Synonyms:
  • N-Boc-3-pyrolidinone
  • 3,5-Dichloro-4-Formyl Pydidine
  • 1-tert-Butoxycarbonyl-3-pyrrolidone
  • 1-N-Boc-3-pyrrolidinone ,98%
  • 1,1-DiMethylethyl 3-Oxopyrrolidine-1-carboxylate
  • N-BOC-3-Pyrrolodinone
  • 1-Boc-3-pyrrolidone 1-tert-Butoxycarbonyl-3-pyrrolidinone 1-Boc-3-pyrrolidinone tert-Butyl 3-Oxopyrrolidine-1-carboxylate 3-Oxopyrrolidine-1-carboxylic Acid tert-Butyl Ester
  • Pyrrolidin-3-one, N-BOC protected 97%
CAS:
101385-93-7
MF:
C9H15NO3
MW:
185.22
EINECS:
600-204-5
Product Categories:
  • Omarigliptin intermediates
  • CHIRAL CHEMICALS
  • pharmacetical
  • Benzenes
  • Aliphatics
  • Heterocycles
  • Amines and Anilines
  • Carbonyl Compounds
  • Pyrrolidines
  • Pyrrole&Pyrrolidine&Pyrroline
Mol File:
101385-93-7.mol
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N-Boc-3-pyrrolidinone Chemical Properties

Melting point:
34-38 °C (lit.)
Boiling point:
270.9±33.0 °C(Predicted)
Density 
1.133±0.06 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Dichloromethane, Ethyl Acetate, Methanol
pka
-1.79±0.20(Predicted)
form 
Low Melting Solid
color 
White to yellow to orange
Water Solubility 
Insoluble in water.
InChIKey
JSOMVCDXPUXKIC-UHFFFAOYSA-N
CAS DataBase Reference
101385-93-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-37/38-41-36/37/38-20/21/22
Safety Statements 
26-36/37/39-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29339900

MSDS

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N-Boc-3-pyrrolidinone Usage And Synthesis

Description

N-Boc-3-pyrrolidinone is an organic compound insoluble in water. It is a starting material for the synthesis of spirocyclic tetrahydrofuran and is also used in studies related to the preparation of 5-membered heterocyclic secondary alcohols with carrot as a biocatalyst[1].

Chemical Properties

Brown Oil

Uses

In the Synthesis and antibacterial evaluation of a novel series of rifabutin-like spirorifamycins 1-Boc-3-pyrrolidinone is used.

Uses

Used in a study of asymmetric hydrogen-transfer bioreduction of ketones with Leifsonia alcohol dehydrogenase.

References

[1] NAIRA VIEIRA MACHADO  á. O. Enantioselective reduction of heterocyclic ketones with low level of asymmetry using carrots[J]. Biocatalysis and Biotransformation, 2021. DOI:10.1080/10242422.2021.1879795.

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