trans-3,4-Difluorocinnamic acid Chemical Properties

Melting point:

194-196 °C(lit.)

Boiling point:

281.3±25.0 °C(Predicted)

Density 

1.3056 (estimate)

storage temp. 

2-8°C

solubility 

soluble in Methanol

form 

powder to crystal

pka

4.27±0.10(Predicted)

color 

White to Almost white

BRN 

7370322

CAS DataBase Reference

112897-97-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29163990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

trans-3,4-Difluorocinnamic acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

trans-3,4-Difluorocinnamic Acid is a starting material in the preparation of Ticagrelor (T437700), which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel.

trans-3,4-Difluorocinnamic acid(112897-97-9)Related Product Information

• 4-(Trifluoromethyl)cinnamic acid
• 3,4-Dimethoxycinnamonitrile
• Ethyl cinnamate
• Methyl cinnamate
• Cinnamic acid
• Octyl 4-methoxycinnamate
• 4-Bromocinnamic acid
• Caffeic acid
• trans-2-(3,4-difluorophenyl) cyclopropanecarboxylic acid
• ((3,4-difluorophenyl) ethynyl)triMethylsilane
• 1,3-bis(cis-2-(3,4-difluorophenyl) cyclopropyl)urea
• 3-(3,4-difluorophenyl)prop-2-yn-1-ol
• ethyCyclopropanamine, 2-(3,4-difluorophenyl)-, (1R,2S)- (REACH)
• (E)-Methyl 3-(3,4-difluorophenyl)acrylate
• trans-Methyl 2-(3,4-difluorophenyl) cyclopropanecarboxylate
• (Z)-3-(3,4-difluorophenyl) prop-2-en-1-ol
• trans-2-(3,4-difluorophenyl) cyclopropanaMine
• (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate