4-(Trifluoromethyl)cinnamic acid Chemical Properties

Melting point:

231-233 °C(lit.)

Boiling point:

279.2±35.0 °C(Predicted)

Density 

1.3275 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

powder to crystal

pka

4.21±0.10(Predicted)

color 

White to Almost white

BRN 

2452800

CAS DataBase Reference

16642-92-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29163990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-(Trifluoromethyl)cinnamic acid Usage And Synthesis

Chemical Properties

white crystalline powder

Uses

trans-4-(Trifluoromethyl)cinnamic acid has been employed as internal standard for the determination of A77 1726 (2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide) in plasma by HPLC.

Definition

ChEBI: (E)-4-(trifluoromethyl)cinnamic acid is a member of the class of (trifluoromethyl)benzenes consisting of trans-cinnamic acid having a trifluoromethyl substituent at the para-position. It is a member of cinnamic acids and a member of (trifluoromethyl)benzenes. It is functionally related to a trans-cinnamic acid.

4-(Trifluoromethyl)cinnamic acid(16642-92-5)Related Product Information

• Cinnamic acid
• Benzotrifluoride
• Trifluoromethanesulfonic acid
• (Trifluoromethyl)trimethylsilane
• alpha-Methylcinnamic acid
• 4-Methoxycinnamic acid
• Stearic acid
• Citric acid
• Lithium trifluoromethanesulfonate
• 4-Aminobenzotrifluoride
• Ethyl 2-(Chlorosulfonyl)acetate
• 3-(Trifluoromethyl)benzaldehyde
• 4-Trifluoromethylbenzyl chloride
• Folic acid
• Ascoric Acid
• Trifluoro-p-tolunitrile
• 4-(Trifluoromethylthio)phenol
• 4-Trifluoromethylphenol