1-CHLORO-3-METHOXY-2-PROPANOL Chemical Properties

Boiling point:

171°C

Density 

1,161 g/cm³

refractive index 

1.4463

Flash point:

72°C

storage temp. 

Store below +30°C.

solubility 

Chloroform, DMSO (Sparingly), Methanol (Slightly)

form 

Oily Liquid

pka

13.28±0.20(Predicted)

color 

Clear faintly yellow

PH

5.6 (50g/l, H2O)

BRN 

1697491

Safety Information

Hazard Codes 

Xi

Risk Statements 

20/21/22-36-36/37/38

Safety Statements 

23-26-36/37/39-36

RIDADR 

2810

WGK Germany 

WGK 3 highly water endangering

HS Code 

2909 49 80

PackingGroup 

III

Toxicity

LD50 orally in Rabbit: 340 mg/kg

MSDS

• Language:English Provider:ALFA

1-CHLORO-3-METHOXY-2-PROPANOL Usage And Synthesis

Chemical Properties

Clear faintly yellow oily liquid

Uses

1-Chloro-3-methoxy-2-propanol is used in the synthesis of O-Methylganciclovir (M275440), an analogue of Ganciclovir (G235000) and displays excellent antiviral activity when tested in vivo against herpes simplex virus type 1 infection in mice.

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 275, 1988 DOI: 10.1021/jo00237a009
Synthetic Communications, 24, p. 1959, 1994 DOI: 10.1080/00397919408010203

1-CHLORO-3-METHOXY-2-PROPANOL(4151-97-7)Related Product Information

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