Basic information Safety Supplier Related

TRIPTOPHENOLIDE

Basic information Safety Supplier Related

TRIPTOPHENOLIDE Basic information

Product Name:
TRIPTOPHENOLIDE
Synonyms:
  • Triptophenolide (Hypolide
  • 6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e][2]benzofuran-1-one
  • 6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e]isobenzofuran-1-one
  • Triptophenolide, BR
  • HYPOLIDE
  • TRIPTOPHENOLIDE
  • Triptophenolide, 98%, from Tripterygium wilfordii Hook.f.
  • Hypolide (Triptophenolide)
CAS:
74285-86-2
MF:
C20H24O3
MW:
312.4
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • Heterocycles
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
74285-86-2.mol
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TRIPTOPHENOLIDE Chemical Properties

Melting point:
232-233℃
Boiling point:
490.0±45.0 °C(Predicted)
Density 
1.21
solubility 
DMSO : 100 mg/mL (320.10 mM; Need ultrasonic)
form 
powder
pka
10.63±0.40(Predicted)
color 
Yellowish
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TRIPTOPHENOLIDE Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Begonia, Tripterygium root bark.

Uses

Used for content determination/identification/pharmacological experiments, etc.

Definition

ChEBI: (3bR,9bS)-6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e]isobenzofuran-1-one is an oxo steroid.

Biological Activity

Triptophenolide is a colorless crystal isolated from the ethyl acetate extraction site of Tripterygium wilfordii.

target

TargetValue
AR-WT
()
260 nM
AR -T877A
()
388 nM
AR-F876L
()
480 nM

TRIPTOPHENOLIDESupplier

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BioBioPha Co., Ltd.
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0871-65217109 13211707573;
Email
y.liu@mail.biobiopha.com