DLinDMA
DLinDMA Basic information
- Product Name:
- DLinDMA
- Synonyms:
-
- DLinDMA
- 1,2-Dilinoleyloxy-N,N-dimethyl-3-aminopropane
- 1-Propanamine, N,N-dimethyl-2,3-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]-
- Inhibitor,DLinDMA,inhibit
- N,N-Dimethyl-2,3-bis(((9Z,12Z)-octadeca-9,12-dien-1-yl)oxy)propan-1-amine
- CAS:
- 871258-12-7
- MF:
- C41H77NO2
- MW:
- 616.06
- Mol File:
- 871258-12-7.mol
More
Less
DLinDMA Chemical Properties
- Boiling point:
- 647.8±55.0 °C(Predicted)
- Density
- 0.879±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:100.0(Max Conc. mg/mL);162.32(Max Conc. mM)
Ethanol:3.0(Max Conc. mg/mL);4.87(Max Conc. mM) - form
- Liquid
- pka
- 8.65±0.28(Predicted)
- color
- Colorless to light yellow
- InChIKey
- NFQBIAXADRDUGK-KWXKLSQISA-N
- SMILES
- C(N(C)C)C(OCCCCCCCC/C=C\C/C=C\CCCCC)COCCCCCCCC/C=C\C/C=C\CCCCC
More
Less
DLinDMA Usage And Synthesis
Uses
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery[1].
in vivo
DLinDMA has virtually indistinguishable blood pharmacokinetic profiles in mice[1].
References
[1] Semple SC, et al. Rational design of cationic lipids for siRNA delivery. Nat Biotechnol. 2010 Feb;28(2):172-6. DOI:10.1038/nbt.1602
DLinDMASupplier
Beijing Jin Ming Biotechnology Co., Ltd. Gold
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
InvivoChem Gold
- Tel
- 13549236410
- sales@invivochem.cn
MIDECO Gold
- Tel
- 023-68625073 15723208759
- lidaijun@midecopharm.com
Bide Pharmatech Ltd.
- Tel
- 400-400-164-7117 18317119277
- product02@bidepharm.com
Shanghai Haozhixiang Biotechnology Co., Ltd
- Tel
- 526763801 13301653310
- 526763801@qq.com