GANODERIC ACID C2(SH) Chemical Properties

Density 

1.22±0.1 g/cm3 (20 ºC 760 Torr)

solubility 

Methanol: soluble

form 

A solid

GANODERIC ACID C2(SH) Usage And Synthesis

Chemical Properties

ex Reishi

Uses

(Rac)-Ganoderic acid C2 is the racemate of Ganoderic acid C2 (HY-N1517). Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses anti-tumor, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 μM[[1][2].

References

[1] Guo XY, et al. l characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2013 Mar 5;75:64-73. DOI:10.1016/j.jpba.2012.11.024
[2] Fatmawati S, et al. Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. Planta Med. 2010 Oct;76(15):1691-3. DOI:10.1055/s-0030-1249782

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