BENZYL PHENYL CARBONATE 97 Chemical Properties

Boiling point:

120-130 °C0.5 mm Hg(lit.)

Density 

1.156 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.5490(lit.)

Flash point:

>230 °F

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

clear liquid

color 

Colorless to Almost colorless

Safety Information

Hazard Codes 

Xi

Risk Statements 

41-43

Safety Statements 

26-36/37/39

WGK Germany 

3

HS Code 

29209090

BENZYL PHENYL CARBONATE 97 Usage And Synthesis

Chemical Properties

Colorless to clear yellow liquid

Uses

Benzyl phenyl carbonate can be used to synthesize carbamate protected polyamines.

General Description

Benzyl phenyl carbonate can be synthesized by reacting phenyl chloroformate with benzyl alcohol in the presence of pyridine.

Synthesis

Synthesis of benzyl phenyl carbonate (Synthesis, 2002, 15, 2195-2202) Benzyl alcohol (10.8 g, 100.0 mmol) was dissolved in 100 mL of dichloromethane (CH2Cl2). After the solution was cooled to 0°C, phenyl chloroformate (15.7 g, 100 mmol) was added slowly and dropwise. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, 100 mL of water (H2O) was added, followed by washing twice with 100 mL of 2 M sulfuric acid (H2SO4). The organic phase was separated and dried over anhydrous sodium sulfate (Na2SO4). The solvent was removed by distillation under reduced pressure to give the colorless liquid product benzyl phenyl carbonate (22.5 g, 99% yield). The product was characterized by 1H NMR (CDCl3, 300 MHz): δ= 7.45-7.31 (m, 6H, arylhydrogen), 7.25-7.14 (m, 4H, arylhydrogen), 5.25 (s, 2H, benzylhydrogen).

References

[1] Patent: US2013/203960, 2013, A1. Location in patent: Page/Page column
[2] Patent: US2009/36353, 2009, A1

BENZYL PHENYL CARBONATE 97(28170-07-2)Related Product Information

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• TETRAETHYLENE GLYCOL DI-P-TOSYLATE
• CARBONIC ACID DI-2-PYRIDYL ESTER
• Benzyl chloroformate