Arachidonic Acid-d5 Chemical Properties

storage temp. 

Store at -20°C

solubility 

0.1 M Na2CO3: 1 mg/ml,DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml

form 

Liquid

color 

Colorless to light yellow

Arachidonic Acid-d5 Usage And Synthesis

Uses

Arachidonic acid-d5 is the deuterium labeled Arachidonic acid. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes.

Biological Activity

Arachidonic acid-d5 is intended for use as an internal standard for the quantification of arachidonic acid by GC- or LC-MS. Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways.1 Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.2

References

1.Nixon, A.B., Greene, D.G., and Wykle, R.L.Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophilsBiochim. Biophys. Acta.1300(3)187-196(1996) 2.Burgoyne, R.D., and Morgan, A.The control of free arachidonic acid levelsTrends Biochem. Sci.15(10)365-366(1990)

Arachidonic Acid-d5(123167-26-0)Related Product Information

• Arachidonic Acid methyl ester-d8
• EICOSANOIC-2,2-D2 ACID
• Arachidonic Acid-d5 methyl ester
• YLEARPUNMCCKMP-FBFLGLDDSA-N
• 5,8,11,14-Eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid, (5Z,8Z,11Z,14Z)-