Basic information Safety Supplier Related

UNCARINE E

Basic information Safety Supplier Related

UNCARINE E Basic information

Product Name:
UNCARINE E
Synonyms:
  • allo-Isopteropodine
  • UNCARINE E
  • (7alpha,19alpha,20alpha)-19-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
  • ISOPTEROPODINE
  • (7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
  • 7-Isopteropodine
  • (1R,4aR,10aR)-2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester
  • methyl (1R,4aR,10aR)-1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
CAS:
5171-37-9
MF:
C21H24N2O4
MW:
368.43
Product Categories:
  • standard material,plant extracts
Mol File:
5171-37-9.mol
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UNCARINE E Chemical Properties

Melting point:
209-211 °C
Boiling point:
555.2±50.0 °C(Predicted)
Density 
1.33
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
13.56±0.60(Predicted)
form 
Solid
color 
Pale Yellow to Pale Beige
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Safety Information

HS Code 
2939800000
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UNCARINE E Usage And Synthesis

Description

This alkaloid occurs in several species of Uncaria and yields colourless crystals from MeOH. It is laevorotatory with [α]D - 96° (CHCI3). The structure has been determined by spectroscopic methods.

Uses

Isopteropodine is an alkaloid extract from Uncaria Tomentosathat is believed to possess antiproliferative and pro-apoptotic effects.

Definition

ChEBI: Uncarine E is a member of indolizines.

References

Hart, Johns, Lamberton., Chem. Commun., 87 (1967)
Hemingway, Phillipson., 1. Pharm. Pharmacol., 24, 169P (1972)

UNCARINE ESupplier

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