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FOSINOPRILAT

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FOSINOPRILAT Basic information

Product Name:
FOSINOPRILAT
Synonyms:
  • FOSINOPRILAT
  • fosinoprilicacid
  • Forsinoprilat
  • 4β-Cyclohexyl-1-[[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-L-proline
  • Fosfenopril
  • Fospenopril
  • SQ-27519
  • Fosinopril Related Compound A (25 mg) ((4S)-4-cyclohexyl-[(4-phenylbutyl)phosphinyl]acetyl-L-proline)
CAS:
95399-71-6
MF:
C23H34NO5P
MW:
435.49
Product Categories:
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Aromatics
  • Chiral Reagents
  • Phosphorylating and Phosphitylating Agents
  • Various Metabolites and Impurities
  • Isotopically Labeled Pharmaceutical Reference Standard
Mol File:
95399-71-6.mol
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FOSINOPRILAT Chemical Properties

Melting point:
>3000C
alpha 
D -24° (c = 1 in methanol)
Boiling point:
728.9±60.0 °C(Predicted)
Density 
1.238±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Methanol (Slightly), Water (Slightly)
pka
2.75±0.50(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Safety Information

WGK Germany 
3
HS Code 
2933995300
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FOSINOPRILAT Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

A metabolite of Fosinopril, a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor

Uses

Fosinoprilat (Fosinopril EP Impurity A) is a metabolite of Fosinopril (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor.

Definition

ChEBI: A phosphinic acid-containing N-acyl derivative of (4S)-cyclohexyl-L-proline. An inhibitor of angiotensin converting enzyme (ACE), it is used as the phosphinate ester pro-drug fosinopril for treatment of ypertension and chronic heart failure.

FOSINOPRILATSupplier

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