1,2-Dichloro-3-iodobenzene Chemical Properties

Melting point:

35-36 °C(lit.)

Boiling point:

123-126 °C20 mm Hg(lit.)

Density 

1.9882 (estimate)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Sealed in dry,2-8°C

solubility 

very faint turbidity in Methanol

form 

Crystalline Mass

color 

White

Sensitive 

Light Sensitive

BRN 

2247168

CAS DataBase Reference

2401-21-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-37/39-24/25-36/37/39

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29039990

MSDS

• Language:English Provider:2,3-Dichloro-1-iodobenzene
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1,2-Dichloro-3-iodobenzene Usage And Synthesis

Chemical Properties

white crystalline mass

Uses

1,2-Dichloro-3-iodobenzene is a Iodobenzenes chemical, which has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. 

Synthesis

The general procedure for synthesizing 1,2-dichloro-3-iodobenzene from iodobenzene is as follows: in Example 6, the preparation of dichloroiodobenzene, chlorine gas was passed in a bubbling manner into a solution of iodobenzene (20.4 g; 0.1 mol) dissolved in chloroform (100 ml), while controlling the temperature of the reaction mixture to be maintained at -5 °C. After about 10 minutes, a yellow solid precipitate appeared in the reaction mixture, which was separated by filtration. Subsequently, chlorine gas was continued to be passed into the filtrate until no more yellow solid was produced. All obtained solid portions were combined and dried in air to give 25.9 g (94.2% yield) of the target product 1,2-dichloro-3-iodobenzene.

References

[1] Dalton Transactions, 2014, vol. 44, # 1, p. 119 - 129
[2] Patent: US4203918, 1980, A
[3] Patent: US4358607, 1982, A

1,2-Dichloro-3-iodobenzene(2401-21-0)Related Product Information

• (Diacetoxyiodo)benzene
• Thionyl chloride
• 1,4-Diiodobenzene
• 1,2-Diiodobenzene
• 1,3-Dichloropropene
• Iodobenzene
• Dichloroethane
• Sodium dichloroisocyanurate
• (DICHLOROIODO)-BENZENE
• 1-IODO-2,3,5-TRICHLOROBENZENE
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• 3,5-Dichloro-1-iodobenzene,1,3-DICHLORO-5-IODOBENZENE
• 2,4-DICHLORO-1-IODOBENZENE,1,3-Dichloro-4-iodobenzene, GC 98%,2,4-Dichloro-1-iodobenzene, 98+%,1,3-DICHLORO-4-IODOBENZENE
• 4-Bromo-2,3-dichloroiodobenzene
• 6-IODO-2,4,5-TRICHLOROPHENOL
• 1,2,3,4,5-PENTACHLORO-6-IODOBENZENE
• 1,3-DICHLORO-2-IODOBENZENE