ALPHA-CORTOLONE
ALPHA-CORTOLONE Basic information
- Product Name:
- ALPHA-CORTOLONE
- Synonyms:
-
- 3-ALPHA,17-ALPHA,20-ALPHA,21-TETRAHYDROXY-5-BETA-PREGNAN-11-ONE
- A-cortolone crystalline
- CORTOLONE
- ALPHA-CORTOLONE
- 5-BETA-PREGNAN-3-ALPHA, 17,20-ALPHA, 21-TETROL-11-ONE
- 5BETA-PREGNAN-3ALPHA,17ALPHA,20ALPHA,21-TETROL-11-ONE
- (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3,17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one
- (20S)-3α,17,20,21-Tetrahydroxy-5β-pregnan-11-one
- CAS:
- 516-42-7
- MF:
- C21H34O5
- MW:
- 366.49
- Mol File:
- 516-42-7.mol
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ALPHA-CORTOLONE Chemical Properties
- Melting point:
- 208-209°
- alpha
- D25 +44° (c = 0.5 in ethanol); D28 +34.2° (ethanol)
- Boiling point:
- 564.1±50.0 °C(Predicted)
- Density
- 1.248±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
- pka
- 13.95±0.70(Predicted)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
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ALPHA-CORTOLONE Usage And Synthesis
Uses
α-Cortolone is a human urinary metabolite of Cortisol ((H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
Definition
ChEBI: Cortolone is a 21-hydroxy steroid.
ALPHA-CORTOLONESupplier
Nanjing Shizhou Biology Technology Co.,Ltd
- Tel
- 025-85560043 15850508050
- rose.shi@synzest.com
Energy Chemical
- Tel
- 021-58432009 400-005-6266
- marketing@energy-chemical.com
Nanjing Shizhou Biology Technology Co.,Ltd
- Tel
- 18351873721
- helen.zhang@synzest.com
Shanghai Saikerui Biotechnology Co. , Ltd.
- Tel
- 021-58000709 15900491054
- info@scrbio.com
Shanghai Yifei Biotechnology Co. , Ltd.
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
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ALPHA-CORTOLONE(516-42-7)Related Product Information
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- 5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL
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- ALPHA-CORTOLONE
- CYCLODECANONE
- 3-(HYDROXYMETHYL)CYCLOHEXANONE
- (R)-1,2-HEXADECANEDIOL
- (S)-1,2-DODECANEDIOL
- CYCLOTRIDECANONE
- (S)-1,2-HEXADECANEDIOL
- 5BETA-PREGNANE-3ALPHA,17ALPHA,20ALPHA-TRIOL
- 11-Keto-pregnanetriol
- (R)-(+)-1,2-OCTADECANEDIOL
- 2-HEPTANONE，5-(HYDROXYMETHYL)
- CYCLONONANONE
- (S)-1,2-OCTADECANEDIOL