N-OLEOYLGLYCINE Chemical Properties

Melting point:

77-78 °C

Boiling point:

525.6±43.0 °C(Predicted)

Density 

0.962±0.06 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

DMF: 10 mg/ml; DMSO: 12 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 200 μg/ml

form 

A crystalline solid

pka

3.59±0.10(Predicted)

color 

White to off-white

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

N-OLEOYLGLYCINE Usage And Synthesis

Description

N-Oleoyl glycine is a putative substrate for peptidyl glycine α-amidating enzyme in the biosynthesis of oleoyl amide.

Uses

N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte.

Definition

ChEBI: A fatty acid derivative that is the 9Z-octadecenoyl derivative of glycine.

IC 50

Human Endogenous Metabolite; CB1

References

[1] Wang S, et al. N-Oleoyl glycine, a lipoamino acid, stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. Biochem Biophys Res Commun. 2015 Oct 23;466(3):438-43. DOI:10.1016/j.bbrc.2015.09.046

N-OLEOYLGLYCINE(2601-90-3)Related Product Information

• Deionized water
• N,N'-Ethylenebis(stearamide)
• (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
• Oleamide
• Oleylamine
• Oleoyl Ethanolamide
• N-OLEOYLGLYCINE
• N-ETHYL-9Z-OCTADECENAMIDE