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H-CYS(BZL)-OME HCL

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H-CYS(BZL)-OME HCL Basic information

Product Name:
H-CYS(BZL)-OME HCL
Synonyms:
  • L-Cys(Bzl)-OMe·HCl
  • BENZYL-L-CYSTEINE METHYL ESTER HYDROCHLORIDE
  • H-CYS(BZL)-OME HCL
  • CYSTEINE(BZL)-OME HCL
  • S-BENZYL-L-CYSTEINE METHYL ESTER HYDROCHLORIDE
  • S-BENZYL-L-CYSTEINE METHYL ESTER HYDROCHLORIDE SALT
  • S-benzyl-L-cysteine methyl ester*hydrochloride cr
  • methyl S-benzyl-L-cysteinate hydrochloride
CAS:
16741-80-3
MF:
C11H16ClNO2S
MW:
261.77
EINECS:
240-803-5
Product Categories:
  • Amino Acids and Derivatives
  • Amino Acid Derivatives
  • Amino Acids
Mol File:
16741-80-3.mol
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H-CYS(BZL)-OME HCL Chemical Properties

Melting point:
160-162 °C(Solv: methanol (67-56-1); ethyl ether (60-29-7))
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
color 
White to light yellow
CAS DataBase Reference
16741-80-3(CAS DataBase Reference)
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Safety Information

WGK Germany 
3

MSDS

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H-CYS(BZL)-OME HCL Usage And Synthesis

Chemical Properties

Crystalline

Uses

S-Benzyl-L-cysteine Methyl Ester Hydrochloride is a potential amino acid antagonists in bacteria

Synthesis

67-56-1

3054-01-1

16741-80-3

The general procedure for the synthesis of S-benzyl-L-cysteine methyl ester hydrochloride from methanol and S-benzyl-L-cysteine is as follows: Example 1: Synthesis of OFN(L-cyanocyclopropyl)-3-phenylmethylsulfonyl-2(R)-(2,2,2-trifluoro-1(RS)-thiophen-2-yl-ethylamino)propionamide Step 1: 2(R)-amino-3-phenylmethane-based sulfuric acid (commercially available) (4.01 g, 19.0 mmol) was dissolved in methanol (100 mL), cooled to 0°C and stirred. HCl gas was passed into this solution for 15 min, after which the reaction mixture was sealed and stirring was continued overnight at room temperature. After completion of the reaction, the solvent was evaporated under vacuum to give propyl methyl 2(R)-amino-3-phenylmethane sulfate hydrochloride (4.98 g) in quantitative yield.

References

[1] Patent: WO2005/28429, 2005, A2. Location in patent: Page/Page column 64
[2] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006, vol. 45, # 8, p. 1942 - 1944
[3] European Journal of Medicinal Chemistry, 2012, vol. 55, p. 176 - 187,12
[4] Organic Preparations and Procedures International, 1991, vol. 23, # 1, p. 93 - 102

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