13,14-DIHYDRO-15(R)-PROSTAGLANDIN E1 Chemical Properties

Boiling point:

541.4±35.0 °C(Predicted)

Density 

1.075±0.06 g/cm3(Predicted)

solubility 

DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)

pka

4.77±0.10(Predicted)

13,14-DIHYDRO-15(R)-PROSTAGLANDIN E1 Usage And Synthesis

Uses

13,14-dihydro-15(R)-Prostaglandin E1 (13,14-dihydro-15(R)- PGE1) is an analog of 13,14-dihydro- PGE1 which has the hydroxyl group at C-15 in the unnatural R configuration[1].

Definition

ChEBI: 13,14-dihydro-15(R)-Prostaglandin E1 is a prostanoid.

References

[1] Sinzinger H, et al. PGE1 and 13, 14-dihydro-PGE1 Increase Low-Density Lipoprotein Receptors and Improve Arterial Wall Lipid Metabolism//Prostaglandin E1: New Aspects on Pharmacology, Metabolism and Clinical Efficacy. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991: 39-48.

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