BCN-PEG3-VC-PFP ester
BCN-PEG3-VC-PFP ester Basic information
- Product Name:
- BCN-PEG3-VC-PFP ester
- Synonyms:
-
- BCN-PEG3-VC-PFP ester
- endo BCN-PEG3-VC-PFP Ester
- L-Ornithine, N-[16-(1R,8S)-bicyclo[6.1.0]non-4-yn-9-yl-1,14-dioxo-4,7,10,15-tetraoxa-13-azahexadec-1-yl]-L-valyl-N5-(aminocarbonyl)-, 2,3,4,5,6-pentafluorophenyl ester
- CAS:
- 2353409-45-5
- MF:
- C37H50F5N5O10
- MW:
- 819.81
- Mol File:
- 2353409-45-5.mol
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BCN-PEG3-VC-PFP ester Chemical Properties
- Boiling point:
- 925.6±65.0 °C(Predicted)
- Density
- 1.34±0.1 g/cm3(Predicted)
- solubility
- Soluble in DMSO, DCM, DMF
- pka
- 12.05±0.46(Predicted)
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BCN-PEG3-VC-PFP ester Usage And Synthesis
Description
BCN-PEG3-VC-PFP Ester is a cleavable ADC linker. PFP ester can be reactive with amine-bearing molecule to form stable amide bond. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The BCN group can react with azide-tagged biomolecules.
BCN-PEG3-VC-PFP esterSupplier
Affinity（Wuhan）Ltd. Gold
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- 15841022315
- sales@affinitytech.cn
Beijing Jin Ming Biotechnology Co., Ltd.
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- 010-60605840 18892239720
- psaitong@jm-bio.com
Xi'an Confluore Biological Technology Co., Ltd.
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- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
Abydos Scientific
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- 025-84767922 18936879710
- sales@abydoscientific.com
Alfa Chemistry
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- Info@alfa-chemistry.com