2',3'-DIDEOXY-3'-FLUORO-GUANOSINE Chemical Properties

Melting point:

253-255 °C (decomp)

Boiling point:

633.5±65.0 °C(Predicted)

Density 

2.01±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

pka

14.44±0.10(Predicted)

2',3'-DIDEOXY-3'-FLUORO-GUANOSINE Usage And Synthesis

Uses

Lagociclovir (FLG) is a nucleoside analogue that inhibits wild-type hepatitis B virus (HBV) replication in a human hepatoma cell line permanently expressing HBV[1].

References

[1] Jacquard AC, et al. In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2',3'-dideoxy-3'-fluoroguanosine. Antimicrob Agents Chemother. 2006 Mar;50(3):955-61. DOI:10.1128/AAC.50.3.955-961.2006

2',3'-DIDEOXY-3'-FLUORO-GUANOSINE(92562-88-4)Related Product Information

• Dideoxyinosine
• 2'-Deoxycytidine monohydrate
• 2'-Deoxyadenosine 5'-phosphate
• Guanosine
• Dideoxyadenosine
• 2',3'-Dideoxyguanosine
• 2',3'-DIDEOXY-3'-FLUORO-GUANOSINE
• 3fluoro-3deoxyguanosine