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8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl endo-(±)-formylphenylacetate

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8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl endo-(±)-formylphenylacetate Basic information

Product Name:
8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl endo-(±)-formylphenylacetate
Synonyms:
  • 8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl endo-(±)-formylphenylacetate
  • 8-(1-Methylethyl)-8-azabicyclo[3.2.1]oct-3-yl -formylphenacetate
  • N-Isopropylnortropinyl-formylphenacetate
  • N-ISOPROPYLNORTROPINYL A ORMYLPHENACETATE
  • Benzeneacetic acid, α-formyl-, (3-endo)-8-(1-methylethyl)-8-azabicyclo[3.2.1]oct-3-yl ester
  • N-Isopropylnortropinyl alpha-formylphenacetate
  • (1R,3r,5S)-8-isopropyl-8-azabicyclo[3.2.1]octan-3-yl 3-oxo-2-phenylpropanoate
  • (1R,5S)-8-isopropyl-8-azabicyclo[3.2.1]octan-3-yl 3-oxo-2-phenylpropanoate
CAS:
22235-74-1
MF:
C19H25NO3
MW:
315.41
EINECS:
244-858-6
Mol File:
22235-74-1.mol
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8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl endo-(±)-formylphenylacetate Chemical Properties

Melting point:
203 °C
Boiling point:
421.5±45.0 °C(Predicted)
Density 
1.14±0.1 g/cm3(Predicted)
pka
6.37±0.29(Predicted)
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8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl endo-(±)-formylphenylacetate Usage And Synthesis

Chemical Properties

Light yellow crystals. Melting point 154-160 ℃.

Uses

Used as Intermediate of isopropyl atropine.

Synthesis

8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl endo-(±)-formylphenylacetate was prepared by reacting N-isopropyl nortropine with methyl 2-formyl phenylacetate refluxed in toluene.

8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl endo-(±)-formylphenylacetate Preparation Products And Raw materials

Raw materials

8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl endo-(±)-formylphenylacetateSupplier

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