ChemicalBook > Product Catalog > Organic Chemistry > Organometallic compounds > Organic ruthenium > DICHLOROTRICARBONYLRUTHENIUM (II) DIMER
DICHLOROTRICARBONYLRUTHENIUM (II) DIMER
DICHLOROTRICARBONYLRUTHENIUM (II) DIMER Basic information
- Product Name:
- DICHLOROTRICARBONYLRUTHENIUM (II) DIMER
- Synonyms:
-
- TRICARBONYLDICHLORORUTHENATE (II) DIMER
- TRICARBONYLDICHLORORUTHENIUM(II) DIMER
- DICHLOROTRICARBONYLRUTHENIUM (II) DIMER
- Dichlorotricarbonylruthenium dimer
- ruthenium(II) tricarbonyl chloride dimer
- Dichlorotricarbonylruthenium(II) dimer, min. 98%
- Dichlorotricarbonylruthenium(II) dimer,98%
- Tetrachlorohexacarbonyldiruthenium
- CAS:
- 22594-69-0
- MF:
- C6Cl4O6Ru2
- MW:
- 512
- Product Categories:
-
- metal carbonyl complexes
- Catalysis and Inorganic Chemistry
- Ru Catalysts
- Ruthenium
- Mol File:
- 22594-69-0.mol
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DICHLOROTRICARBONYLRUTHENIUM (II) DIMER Chemical Properties
- Melting point:
- 208°C (dec.)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Soluble in DMSO
- form
- crystal
- color
- off-white
- Water Solubility
- Insoluble in water
- InChIKey
- JYHHJVKGDCZCCL-UHFFFAOYSA-J
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-37/39
- RIDADR
- UN3466
- WGK Germany
- 3
- HazardClass
- 6.1
- PackingGroup
- III
MSDS
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
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DICHLOROTRICARBONYLRUTHENIUM (II) DIMER Usage And Synthesis
Chemical Properties
Off-white to slightly yellow powder
Uses
Tricarbonyldichlororuthenium(II) dimer is used to enhance the coagulation and attenuation of vulnerability to fibrinolysis, modify thrombus growth or disintegration, enhances fibrinogen as a substrate for thrombin, and regulation of ion transport by gasotransmitters. Also used for various pharmacological studies. It is used as a CO donor for reactive oxygen species mediated bacterial killing.
reaction suitability
core: ruthenium
reagent type: catalyst
in vivo
Tricarbonyldichlororuthenium(II) dimer (1-10 mg/kg; oral gavage; single dose) has a protective effect in a rat model of gastric mucosal injury induced by ischemia-reperfusion[3].
| Animal Model: | Acute I/R gastric lesions treated male Wistar rats (250-300 g)[3] |
| Dosage: | 1, 5 or 10 mg/kg |
| Administration: | Oral gavage (i.g.); single dose |
| Result: | Significantly decreased the area of I/R gastric damage and significantly increased GBF at doses of 1 or 5 mg/kg. Significantly increased mRNA expression of HMOX-1 but not HMOX-2 in gastric mucosa and significantly increased blood concentration at dose of 5 mg/kg. Significantly increased gastric mucosal PGE2 content at dose of 5 mg/kg. Significantly decreased mRNA expression of iNOS but not eNOS in gastric mucosa at dose of 5 mg/kg. Significantly decreased 8-hydroxyguanozine (8-OHG) concentration in gastric mucosa at dose of 5 mg/kg. Decreased the expression of pro- and anti-inflammatory markers' mRNA and proteins at dose of 5 mg/kg. |
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