BAPTA, TETRASODIUM SALT Chemical Properties

storage temp. 

−20°C

solubility 

H₂O: 10 mg/mL, clear, faintly yellow

form 

Off-white solid

Water Solubility 

Soluble in water.

BRN 

8818619

InChIKey

ZWSMLJACYSGFKD-UHFFFAOYSA-J

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

24/25-36-26

WGK Germany 

3

F 

8-10-21

HS Code 

29189900

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

BAPTA, TETRASODIUM SALT Usage And Synthesis

Chemical Properties

beige powder

Uses

Suitable as Ca2+-indicator (fluorescence suppressed by Ca2+). Chelator with a greater selectivity for calcium compared to magnesium.

Uses

BAPTA, Tetrasodium Salt is a selective calcium chelator with 105-fold greater affinity for Ca2+ than for Mg2+. This product is a high quality and sensitive compound for calcium signaling studies, investigation of signal transduction and apoptotic cascades, and neuroscience research.

General Description

Ca²⁺-chelator exhibiting a 10⁵-fold greater affinity for Ca²⁺ (110 nM) than for Mg²⁺. After BAPTA complexes with Ca²⁺, the UV spectrum shifts from 254 to 279 nm at pH >6.0. Useful for spectrophotometric monitoring of extracellular Ca²⁺ levels, especially transient phenomena, because of its insensitivity to pH. Has been used for the measurement and control of Ca²⁺ levels in eggs, chromaffin cells, muscle cells, retinal cells, and pancreatic cells. In conjunction with certain formazan dyes, BAPTA can be used in a colorimetric assay for Mg²⁺. Has neuroprotective effects in vitro against excitotoxic damage and spontaneous recurrent seizures, such as epilepsy.

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