Etamsylate
Etamsylate Basic information
- Product Name:
- Etamsylate
- Synonyms:
-
- altodor
- e141
- eselin
- md141
- 2,5-dihydroxy-benzenesulfonicacicompd.withdiethylamine
- 2,5-dihydroxy-benzenesulfonicacicompd.withn-ethylethanamine(1:1)
- 2,5-dihydroxybenzenesulfonicacidcompd.withn-ethylethanamine
- 2,5-DihydroxybenzenesulfonicacidcompdwithN-ethylethanamine
- CAS:
- 2624-44-4
- MF:
- C10H17NO5S
- MW:
- 263.31
- EINECS:
- 220-090-7
- Product Categories:
-
- Other APIs
- For the prevention and treatment of bleeding before surgery, but for intestinal bleeding, bleeding and urinary tract bleeding, etc
- Amines
- Aromatics
- Intermediates & Fine Chemicals
- API
- Pharmaceuticals
- Sulfur & Selenium Compounds
- 2624-44-4
- Mol File:
- 2624-44-4.mol
Etamsylate Chemical Properties
- Melting point:
- 125°
- Density
- 1.3441 (rough estimate)
- refractive index
- 1.5060 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Very soluble in water, freely soluble in methanol, soluble in anhydrous ethanol, practically insoluble in methylene chloride.
- color
- White to Pale Red
- Merck
- 14,3722
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C6H6O5S.C4H11N/c7-4-1-2-5(8)6(3-4)12(9,10)11;1-3-5-4-2/h1-3,7-8H,(H,9,10,11);5H,3-4H2,1-2H3
- InChIKey
- HBGOLJKPSFNJSD-UHFFFAOYSA-N
- SMILES
- C1(S(=O)(=O)O)=CC(=CC=C1O)O.N(CC)CC
- CAS DataBase Reference
- 2624-44-4(CAS DataBase Reference)
- EPA Substance Registry System
- Ethamsylate (2624-44-4)
MSDS
- Language:English Provider:Etamsylate
Etamsylate Usage And Synthesis
Chemical Properties
White Solid
Uses
Haemostatic / Anti Coagulant
Uses
Hemostatic;prostaglandin synthesis inhibitor
Definition
ChEBI: Etamsylate is a sulfonic acid derivative and an organosulfur compound.
Mechanism of action
Etamsylate is an antihaemorrhagic and vasoprotective agent. It increases platelet adhesiveness and capillary vascular wall resistance, thereby reducing capillary exudation and blood loss.
Clinical Use
Short-term treatment of blood loss in menorrhagiaProphylaxis of surgical bleeding (unlicensed)
Side effects
Significant: Hypotension (parenteral). Rarely, severe hypersensitivity reaction, including anaphylaxis.
Blood and lymphatic system disorders: Parenteral: Rarely, neutropenia, agranulocytosis, thrombocytopenia.
Gastrointestinal disorders: Nausea, vomiting, diarrhoea, abdominal pain or discomfort.
General disorders and administration site conditions: Asthenia (parenteral). Rarely, fever.
Musculoskeletal and connective tissue disorders: Rarely, arthralgia.
Nervous system disorders: Headache.
Skin and subcutaneous tissue disorders: Rash.
Vascular disorders: Rarely, thromboembolism (parenteral).
Metabolism
Etamsylate is excreted unchanged, mainly in the urine.
Etamsylate Preparation Products And Raw materials
Raw materials
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Etamsylate(2624-44-4)Related Product Information
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- Diethylamine hydrochloride
- ETAMSYLATE FOR INJECTION
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