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Trifluoromethanesulfonamide

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Trifluoromethanesulfonamide Basic information

Product Name:
Trifluoromethanesulfonamide
Synonyms:
  • Trifluoromethanesulfonamide,96%
  • trifluoromethylsulfonamide
  • Trifluoromethanesulphonamide 98%
  • Trifluoromethanesulphonamide98%
  • Trifluoromethanesulphonamide, tech. 96%
  • Trifluoromethanesulfonimidic acid
  • TrifluoroMethanesulfonaMide 95%
  • TRIFLAMIDE
CAS:
421-85-2
MF:
CH2F3NO2S
MW:
149.09
EINECS:
431-270-1
Product Categories:
  • Pyridines
  • Bioactive Small Molecules
  • Building Blocks
  • Cell Biology
  • Chemical Synthesis
  • Organic Building Blocks
  • Organic Building Blocks
  • Sulfonamides/Sulfinamides
  • Sulfur Compounds
  • Sulfur Compounds
  • T
Mol File:
421-85-2.mol
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Trifluoromethanesulfonamide Chemical Properties

Melting point:
120-124 °C(lit.)
Boiling point:
164.6±45.0 °C(Predicted)
Density 
1.730±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
6.37±0.60(Predicted)
color 
Off-White
Water Solubility 
Soluble in water.
BRN 
1812099
InChI
InChI=1S/CH2F3NO2S/c2-1(3,4)8(5,6)7/h(H2,5,6,7)
InChIKey
KAKQVSNHTBLJCH-UHFFFAOYSA-N
SMILES
C(F)(F)(F)S(N)(=O)=O
CAS DataBase Reference
421-85-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
Hazard Note 
Harmful
HS Code 
29350090

MSDS

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Trifluoromethanesulfonamide Usage And Synthesis

Reaction

Trifluoromethanesulfonamide can react with paraformaldehyde in sulfuric acid to give open chain and cyclic condensation products, or in ethyl acetate to give oxy-methylated products.

Chemical Properties

White to off-white solid

Uses

Trifluoromethanesulfonamide is used as an intermediate in synthetic chemistry. It is used in the preparation of specific inhibitors of mammalian secreted phospholipases A2. It is also involved in the synthesis of ecicosanoids.

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