5-Fluoro-1,3-isobenzofurandione Chemical Properties

Melting point:

75-79 °C (lit.)

Boiling point:

148°C 20mm

Density 

1.55

Flash point:

>93°C

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

solubility 

Soluble in sodium hydroxide.

form 

powder to crystal

color 

White to Almost white

Sensitive 

Moisture Sensitive

BRN 

131281

InChI

InChI=1S/C8H3FO3/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3H

InChIKey

XVMKZAAFVWXIII-UHFFFAOYSA-N

SMILES

C1(=O)C2=C(C=C(F)C=C2)C(=O)O1

CAS DataBase Reference

319-03-9(CAS DataBase Reference)

EPA Substance Registry System

1,3-Isobenzofurandione, 5-fluoro- (319-03-9)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38-42/43

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

2

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

IRRITANT, MOISTURE SENSITIVE

PackingGroup 

Ⅲ

HS Code 

29173990

MSDS

• Language:English Provider:5-Fluoro-1,3-isobenzofurandione
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

5-Fluoro-1,3-isobenzofurandione Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

4-Fluorophthalic anhydride is used in the preparation of 5-fluoro-2-pyridin-3-ylmethyl-isoindole-1,3-dione by reacting with C-pyridin-3-yl-methylamine.

Uses

4-Fluorophthalic anhydride can be used as a reactant to prepare:

• 4-amino substituted phthalimides applicable as potential fluorescent probes and fluorescent bioactive compounds.
• 4,4′-bis(4-fluorophthalimido)diphenyl ether monomer, which is used in the synthesis of cardo polymers via nucleophilic substitution polymerization reaction.
• Asymmetric polyimides by a solution polycondensation reaction.

General Description

4-Fluorophthalic anhydride is a fluorinated building block commonly used in chemical synthesis for the preparation of polyimide, pesticides, herbicides, and fungicides. It can be synthesized by treating 4-chlorophthalic anhydride with potassium fluoride.

5-Fluoro-1,3-isobenzofurandione(319-03-9)Related Product Information

• Phthalic acid
• 3-Nitrophthalic anhydride
• Phthalic anhydride
• Biphenyl-4,4'-dicarboxylic acid
• 4-Fluoro-1,1'-biphenyl
• 4-Fluorophthalic acid
• 4-Fluoro-1,3-isobenzofurandione
• 3,6-DIFLUOROPHTHALIC ANHYDRIDE
• AKOS 92366
• 5-Fluoro-1,3-isobenzofurandione
• 4,5-DIFLUOROPHTHALIC ANHYDRIDE
• Tetrafluorophthalic anhydride
• AKOS 92364