BREVETOXIN PBTX-3 Chemical Properties

Density 

1.190±0.06 g/cm3(Predicted)

storage temp. 

-20C

solubility 

DMSO: soluble,Ethanol: soluble,Methanol: soluble

form 

Solid

pka

13.78±0.70(Predicted)

color 

White to off-white

Safety Information

RIDADR 

3172

RTECS 

XW5885000

HazardClass 

6.1(a)

PackingGroup 

I

BREVETOXIN PBTX-3 Usage And Synthesis

General Description

Lipid-soluble polyether marine toxin produced by the red tide dinoflagellate, Ptychodiscus brevis, found along the Gulf Coast of Florida. Voltage-dependent Na⁺ channel activator that causes contractile paralysis in animal models by binding to a unique site on these channels. The excitatory action of brevetoxins on nerve and muscle membranes is responsible for a wide spectrum of the toxic effects, including massive transmitter release from nerve endings, muscle fasciculations, and ventricular fibrillation. The toxin does not bind to either tetrodotoxin or aconitine/veratridine sites.

Biochem/physiol Actions

Primary TargetVoltage-dependent Na+ channel activator

Safety Profile

A poison by ingestion, intraperitoneal, and intravenous routes. When heated to decomposition it emits acrid smoke and irritating vapors.

BREVETOXIN PBTX-3(85079-48-7)Related Product Information

• 3,6,9,12-tetraoxatetradecan-1-ol
• CIS-2-METHYL-7-OCTADECENE
• 2-(2-Ethoxyethoxy)ethyl acrylate
• HEPTAETHYLENE GLYCOL MONODODECYL ETHER
• C10 E8
• Decaethylene glycol
• C16E4
• TRIETHYLENE GLYCOL MONOHEXADECYL ETHER*
• C18E3
• Octadecyl acrylate
• Hexaethylene glycol
• Nonaethylene glycol
• BEHENYL ACRYLATE
• DECAETHYLENE GLYCOL MONOMETHYL ETHER
• PENTAETHYLENE GLYCOL MONOHEXADECYL ETHER
• TRI(PROPYLENE GLYCOL) PROPYL ETHER
• TETRAETHYLENE GLYCOL DIBUTYL ETHER
• HEPTAETHYLENE GLYCOL