1-PHENYL-2-BUTANONE Chemical Properties

Melting point:

72-73 °C

Boiling point:

109-112 °C/15 mmHg (lit.)

Density 

0.998 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.512(lit.)

Flash point:

195 °F

storage temp. 

2-8°C

form 

Liquid

color 

Clear colorless

BRN 

1100022

LogP

2.279 (est)

CAS DataBase Reference

1007-32-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

WGK Germany 

3

HS Code 

29143990

MSDS

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1-PHENYL-2-BUTANONE Usage And Synthesis

Chemical Properties

Pale yellow oily liquid

Uses

1-Phenyl-2-butanone is a building block that has been shown to have sedative activities in mice.

Uses

1-Phenyl-2-butanone was used in the preparation of 1-bromo-1-phenyl-2-butanone. It was used as solute to evaluate the hydroxyl group-solvent and carbonyl group-solvent specific interactions in acetonitrile/water mixtures using the alltima C₁₈ stationary phase by HPLC.

Synthesis Reference(s)

Tetrahedron Letters, 23, p. 4167, 1982 DOI: 10.1016/S0040-4039(00)88377-X

Purification Methods

Purify the ketone by fractionation using an efficient column. It can be converted into the oxime which is distilled, b 117-118o/2mm, 145-146o/15mm, d 25 1.036, n D 1.5363; decompose the oxime, and the ketone is redistilled. It can also be purified via the semicarbazone which has m 154-155o. [Meyers et al. J Am Chem Soc 77 5655 1955, Hass et al. J Org Chem 15 8 1950, Beilstein 7 IV 712.]

1-PHENYL-2-BUTANONE(1007-32-5)Related Product Information

• beta-Tetralone
• DIPHENYLCYCLOPROPENONE
• 6,7-Dimethoxy-2-tetralone
• 7-Methoxy-2-tetralone
• Tetraphenylcyclopentadienone
• 4-Methyl-1-phenyl-2-pentanone
• 1-METHYL-2-TETRALONE
• 2-(3-METHOXYPHENYL)CYCLOHEXANONE
• 2-PHENYLCYCLOHEXANONE
• 1,3-Diphenylacetone
• 6-Methoxy-2-tetralone
• 2-DIPHENYLACETYL-1,3-INDANDIONE-1-HYDRAZONE
• Fluorescamine
• 4-CHLORO-1-PHENYL-1-BUTANONE
• 4-[4-(beta-D-Glucopyranosyloxy)phenyl]-2-butanone
• 2-Bromo-1-(4-fluorophenyl)-1-butanone
• Timiperone
• 3,4-(METHYLENEDIOXY)BENZYLIDENEACETONE