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ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Pharmaceutical Impurity Reference Standards >  5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Basic information

Product Name:
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Synonyms:
  • Nevirapine Related CoMpound A
  • Nevirapine Related Compound A (15 mg) (5,11-dihydro-6H-11-ethyl-4-methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one)
  • BIRH 414
  • 11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • 11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
  • Nevirapine EP Impurity A
  • BIRH 414 BS
CAS:
133627-17-5
MF:
C14H14N4O
MW:
254.29
Product Categories:
  • Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
133627-17-5.mol
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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Chemical Properties

Melting point:
212-214℃ (1,2-dichloroethane )
Boiling point:
389.8±42.0 °C(Predicted)
Density 
1.224±0.06 g/cm3(Predicted)
pka
12.05±0.20(Predicted)
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Safety Information

HS Code 
2933997500
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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Usage And Synthesis

Uses

BIRH 414 is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of wild-type human immunodeficiency virus type 1. BIRH 414 was also shown to exhibit binding affinity towards HIV-1 reverse transcriptase enzyme. This is also an impurity found in Nevirapine (N391275).

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-oneSupplier

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