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(S)-(-)-1-Phenylethyl isocyanate

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(S)-(-)-1-Phenylethyl isocyanate Basic information

Product Name:
(S)-(-)-1-Phenylethyl isocyanate
Synonyms:
  • Isocyanic Acid (S)-(-)-alpha-Methylbenzyl Ester Isocyanic Acid (S)-(-)-1-Phenylethyl Ester (S)-(-)-1-Phenylethyl Isocyanate
  • (S)-(-)-α-Methylbenzyl Isocyanate
  • (S)-(-)-alpha-Methylbenzyl isocyanate 99%
  • (S)-(-)-α-Methylbenzyl isocyanate, for chiral derivatization
  • Tris(pentafluorophenyl)borane(S)-(-)-1-Phenylethylisocyanate
  • (S)-(-)-&alpha
  • [(1S)-1-Isocyanatoethyl]benzene
  • (S) METHYL BENZYLISOCYANATE
CAS:
14649-03-7
MF:
C9H9NO
MW:
147.17
EINECS:
238-698-6
Product Categories:
  • chiral
  • Analytical Chemistry
  • Chiral Building Blocks
  • e.e. / Absolute Configuration Determination (NMR)
  • e.e. Determination (HPLC Labeling Reagents)
  • Enantiomer Excess & Absolute Configuration Determination
  • for Resolution of Alcohols & Thiols
  • for Resolution of Bases
  • Isocyanates (Chiral)
  • Optical Resolution
  • Synthetic Organic Chemistry
Mol File:
14649-03-7.mol
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(S)-(-)-1-Phenylethyl isocyanate Chemical Properties

Melting point:
65 °C
Boiling point:
55-56 °C2.5 mm Hg(lit.)
alpha 
-10 º (NEAT)
Density 
1.045 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.5145(lit.)
Flash point:
150 °F
storage temp. 
2-8°C
form 
Liquid
color 
Clear colorless to pale yellow
optical activity
[α]20/D 10°, neat
Water Solubility 
Decomposition
Sensitive 
Moisture Sensitive
BRN 
4230972
InChIKey
JJSCUXAFAJEQGB-QMMMGPOBSA-N
CAS DataBase Reference
14649-03-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,T+,T
Risk Statements 
36/37/38-42-26-23
Safety Statements 
23-26-36-45-24/25
RIDADR 
UN 2206 6.1/PG 2
WGK Germany 
3
3-10-21
HazardClass 
6.1
PackingGroup 
III
HS Code 
29291090

MSDS

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(S)-(-)-1-Phenylethyl isocyanate Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

(S)-(-)-1-Phenylethyl isocyanate act by inhibition of cell proliferation and induction of apoptosis. It helps to prevent lung cancer and esophageal cancer. It is a fine chemical intermediate.

General Description

(S)-(-)-α-Methylbenzyl isocyanate is a commonly used chiral derivatizing agent for the resolution of enantiomers.

Purification Methods

Purify the isocyanates by fractional distillation under a vacuum. With ammonia

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