D-(+)-Camphoric acid Chemical Properties

Melting point:

186-189 °C

alpha 

46.5 º (c=10, C2H5OH)

Boiling point:

297.96°C (rough estimate)

Density 

1.1860

refractive index 

1.4459 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)

form 

Crystalline Powder

pka

pK1: 4.57;pK2: 5.10 (25°C)

color 

White

optical activity

[α]20/D 46°, c = 1 in ethanol

Water Solubility 

0.8 g/100 mL

Merck 

14,1733

BRN 

2050204

CAS DataBase Reference

124-83-4(CAS DataBase Reference)

NIST Chemistry Reference

D-camphoric acid(124-83-4)

EPA Substance Registry System

1,3-Cyclopentanedicarboxylic acid, 1,2,2-trimethyl-, (1R,3S)- (124-83-4)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

Safety Statements 

24/25

WGK Germany 

2

TSCA 

Yes

HS Code 

29172090

MSDS

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D-(+)-Camphoric acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

D-(+)-Camphoric acid is used primarily as a reagent in syntheses of crystalline structures. It is used in the preparation of polymeric transition metal dipyridylamine D-camphorate complexes.

Uses

(1R,3S)-(+)-Camphoric acid may be used in the preparation (1R,2S,3R,5S)-2,3-dibenzyl-1,8,8-trimethyl-3-thianiumbicyclo[3.2.1]octane perchlorate. It reacts with uranyl nitrate in pyridine(py) or py/methanol(MeOH) to form novel uranyl-organic assemblages.

Definition

ChEBI: (?)-Camphoric acid is a dicarboxylic acid.

General Description

Camphoric acid is a diacid, generally prepared by the oxidation of terpene (+)-camphor. It can be used as a chirality inducing agent in some organic reactions.

storage

+4°C

Purification Methods

Purify the acid by re-precipitation from an alkaline solution by HCl, filter it off, and recrystallise it from water several times, rejecting the first crop. It forms leaflets from EtOH and Me2CO and H2O and is insoluble in CHCl3. Its solubility in H2O is 0.8% at 25o and 10% at 100o, 50% in EtOH and 5% in ethylene glycol. The (±)-acid has m 202-203o. The (+)-1-methyl ester has m 86o (from pet ether) [] 20 +45o (c 4, EtOH), and the (+)-3-methyl ester has m 77o (from pet ether) []17.5 +53.9o (c 3, EtOH). [Rupe & Thommen Helv Chim Acta 30 933

D-(+)-Camphoric acid(124-83-4)Related Product Information

• Citric acid
• (+/-)-10-CAMPHORSULFONIC ACID SODIUM SALT
• DL-Camphor
• Camphor
• Bromocyclopentane
• Cyclopentane
• Ethyl 2-(Chlorosulfonyl)acetate
• Methylcyclopentane
• Hyaluronic acid
• Cyclopentyl chloride
• Trimethyl borate
• Stearic acid
• (1R)-(-)-10-Camphorsulfonic acid
• Folic acid
• White camphor oil
• LEVOCARNITINE RELATED COMPOUND A (100 MG) (3-CARBOXY-N,N,N-TRIMETHYL-2-PROPEN-1-AMINIUM CHLORIDE)
• 4-CHLORO-3-HYDROXY BUTYRONITRILE
• Levocarnitine iMpurity