Agomelatine Impurity 1 Chemical Properties

Boiling point:

451.3±45.0 °C(Predicted)

Density 

1.075±0.06 g/cm3(Predicted)

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

16.23±0.46(Predicted)

color 

Off-White to Pale Yellow

Agomelatine Impurity 1 Usage And Synthesis

Uses

3,4-Dihydroagomelatine is an impurity of Agomelatine (A430000) which is a melatoninergic agonist and selective antagonist of 5-HT2C receptors and used in the treatment of major depressive disorder. Agomelatine Impurity 1

Agomelatine Impurity 1(1352139-51-5)Related Product Information

• (E)-2-(7-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethan-1-amine
• 7-METHOXY-1-NAPHTHOL
• 2-(7-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)ethan-1-amine
• Desacetyl-7-desMethyl AgoMelatine HydrobroMide
• 1-Hydroxy-7-Methoxy-1,2,3,4-tetrahydronaphthalene
• 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride
• 7-DesMethyl-3-hydroxyagoMelatine
• (E)-N-(2-(7-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethyl)acetamide
• 2-(7-Hydroxy-1-naphthyl)ethylaMine
• 2-(7-methoxy-3,4-dihydronaphthalen-1-yl)ethan-1-amine
• 2-(7-Methoxynaphthalen-1-yl)acetamide
• 7-DesMethylagoMelatine
• AgoMelatine-D6
• 1-NaphthaleneacetaMide, 1,2,3,4-tetrahydro-7-Methoxy-
• AGOMELATINE
• 3-Hydroxy Agomelatine
• AcetaMide, N,N-bis[2-(7-Methoxy-1-naphthalenyl)ethyl]-
• N-acetyl-N-(2-(7-Methoxynaphthalen-1-yl)ethyl)acetaMide