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Perfluorodecalin

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Perfluorodecalin Basic information

Product Name:
Perfluorodecalin
Synonyms:
  • 1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-Octadecafluorodecahydronaphthalene
  • decahydrooctadecafluoro-naphthalen
  • F-DC
  • Naphthalene, octadecafluorodecahydro-
  • octadecafluorodecahydro-naphthalen
  • Octadecafluorodecaline
  • perflunafene
  • Perfluorodecalin (PFD, Perflunafene, Octadecaflourodecahydronaphtalene (CIS+Trans), 95% (Perftordecalin))
CAS:
306-94-5
MF:
C10F18
MW:
462.08
EINECS:
206-192-4
Product Categories:
  • Fluorinated Building Blocks
  • Halogenated Hydrocarbons
  • Alkyl Fluorinated Building Blocks
  • Organic Building Blocks
  • Organic Fluorinated Building Blocks
  • Other Fluorinated Organic Building Blocks
  • Purine
  • Fluorous Chemistry
  • Fluorous Solvents
  • Synthetic Organic Chemistry
  • Aryl
  • Building Blocks
  • C9 to C12
  • Chemical Synthesis
  • organofluorine compounds
Mol File:
306-94-5.mol
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Perfluorodecalin Chemical Properties

Melting point:
-10 °C (lit.)
Boiling point:
142 °C (lit.)
Density 
1.908 g/mL at 25 °C (lit.)
vapor density 
17.5 (vs air)
vapor pressure 
8.8hPa at 25℃
refractive index 
n20/D 1.3145(lit.)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
form 
Liquid
color 
Clear colorless
Specific Gravity
1.908
Water Solubility 
Insoluble
Merck 
14,4183
BRN 
2067113
InChIKey
UWEYRJFJVCLAGH-UHFFFAOYSA-N
LogP
5.02-666 at 25℃
CAS DataBase Reference
306-94-5(CAS DataBase Reference)
NIST Chemistry Reference
Perflunafene(306-94-5)
EPA Substance Registry System
Perfluorodecalin (306-94-5)
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Safety Information

Hazard Codes 
Xi,F
Risk Statements 
10
Safety Statements 
23-24/25-41-16
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
RTECS 
QJ3175000
Hazard Note 
Irritant
TSCA 
T
HazardClass 
3.2
PackingGroup 
III
HS Code 
29038900
Toxicity
LD50 ivn-mus: 50 mg/kg PGPKA8 27(10),8,82

MSDS

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Perfluorodecalin Usage And Synthesis

Description

Perfluorodecalin (PFD) is a chemically and biologicallyinert biomaterial and, as many perfluorocarbons, is alsohydrophobic, radiopaque and has a high solute capacity forgases such as oxygen.
Perfluorodecalin is a fluorocarbon and derivative of decalin, and used in cosmetics and beauty products as to dissolve and deliver oxygen to the skin in formulas (Wikipedia). It is also used as a skin conditioning agent, detangler, and solvent in some formulas. Perfluorodecalin's ability to dissolve oxygen is thought to revitalize skin and reduce wrinkles, increasing the partial pressure of oxygen (pO2), according to research.
Some studies have shown that formulas that include Perflurodecalin improve the skin's barrier function resulting in increased moisturizing efficacy. However, there are no studies to prove that added oxygen can actually repair wrinkled skin or prevent lines from forming. Conversely, too much oxygen can enhance the number of unstable oxygen molecules which cause free radical damage.

Chemical Properties

clear colourless liquid

Uses

Perfluorodecalin is a fluorous solvent generally used as a primary component of the fluorous biphasic system (FBS) or the fluorous multiphasic system (FMS) in synthetic chemistry. It is also used as an additive to increase oxygen solubility in fermentation media.

Uses

Perfluorodecalin is used as a building block reagent as well maintains ability to dissolve gases such as oxygen and increase oxygen to a location allowing for medicinal uses such as preserving tissue after pancreas transplants.

Definition

ChEBI: A fluorocarbon that is decalin in which every hydrogen is replaced by fluorine. Capable of dissolving large quantities of oxygen, it has been used as the basis of an artificial blood substitute.

Safety Profile

Poison by intravenous route. When heated to decomposition it emits toxic vapors of Fí.

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