Perfluorodecalin Chemical Properties

Melting point:

-10 °C (lit.)

Boiling point:

142 °C (lit.)

Density 

1.908 g/mL at 25 °C (lit.)

vapor density 

17.5 (vs air)

vapor pressure 

8.8hPa at 25℃

refractive index 

n20/D 1.3145(lit.)

Flash point:

>230 °F

storage temp. 

Store below +30°C.

form 

Liquid

color 

Clear colorless

Specific Gravity

1.908

Water Solubility 

Insoluble

Merck 

14,4183

BRN 

2067113

InChIKey

UWEYRJFJVCLAGH-UHFFFAOYSA-N

LogP

5.02-666 at 25℃

CAS DataBase Reference

306-94-5(CAS DataBase Reference)

NIST Chemistry Reference

Perflunafene(306-94-5)

EPA Substance Registry System

Perfluorodecalin (306-94-5)

Safety Information

Hazard Codes 

Xi,F

Risk Statements 

10

Safety Statements 

23-24/25-41-16

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

RTECS 

QJ3175000

Hazard Note 

Irritant

TSCA 

T

HazardClass 

3.2

PackingGroup 

III

HS Code 

29038900

Toxicity

LD50 ivn-mus: 50 mg/kg PGPKA8 27(10),8,82

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Perfluorodecalin Usage And Synthesis

Description

Perfluorodecalin (PFD) is a chemically and biologicallyinert biomaterial and, as many perfluorocarbons, is alsohydrophobic, radiopaque and has a high solute capacity forgases such as oxygen.
Perfluorodecalin is a fluorocarbon and derivative of decalin, and used in cosmetics and beauty products as to dissolve and deliver oxygen to the skin in formulas (Wikipedia). It is also used as a skin conditioning agent, detangler, and solvent in some formulas. Perfluorodecalin's ability to dissolve oxygen is thought to revitalize skin and reduce wrinkles, increasing the partial pressure of oxygen (pO2), according to research.
Some studies have shown that formulas that include Perflurodecalin improve the skin's barrier function resulting in increased moisturizing efficacy. However, there are no studies to prove that added oxygen can actually repair wrinkled skin or prevent lines from forming. Conversely, too much oxygen can enhance the number of unstable oxygen molecules which cause free radical damage.

Chemical Properties

clear colourless liquid

Uses

Perfluorodecalin is a fluorous solvent generally used as a primary component of the fluorous biphasic system (FBS) or the fluorous multiphasic system (FMS) in synthetic chemistry. It is also used as an additive to increase oxygen solubility in fermentation media.

Uses

Perfluorodecalin is used as a building block reagent as well maintains ability to dissolve gases such as oxygen and increase oxygen to a location allowing for medicinal uses such as preserving tissue after pancreas transplants.

Definition

ChEBI: A fluorocarbon that is decalin in which every hydrogen is replaced by fluorine. Capable of dissolving large quantities of oxygen, it has been used as the basis of an artificial blood substitute.

Safety Profile

Poison by intravenous route. When heated to decomposition it emits toxic vapors of Fí.

Perfluorodecalin(306-94-5)Related Product Information

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