Basic information Safety Supplier Related

(R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE

Basic information Safety Supplier Related

(R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE Basic information

Product Name:
(R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE
Synonyms:
  • p-Toluenesulfonic acid [(R)-2,2-dimethyl-1,3-dioxolane-4β-yl]methyl ester
  • p-Toluenesulfonic acid [R,(-)]-2,2-dimethyl-1,3-dioxolan-4-ylmethyl ester
  • p-Toluenesulfonic acid [R,(-)]-2,2-dimethyl-1,3-dioxolane-4-ylmethyl ester
  • (R)-(-)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulfonate,97%
  • p-Toluenesulfonic acid ((4R)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl ester
  • Toluene-4-sulfonic acid ((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)methyl ester
  • D-α,β-Isopropylideneglycerol-γ-tosylate
  • [(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 4-methylbenzene-1-sulfonate
CAS:
23788-74-1
MF:
C13H18O5S
MW:
286.34
Product Categories:
  • chiral
  • Chiral Building Blocks
  • Dioxanes & Dioxolanes
  • Dioxolanes
  • Glycidyl Compounds, etc. (Chiral)
  • Synthetic Organic Chemistry
Mol File:
23788-74-1.mol
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(R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE Chemical Properties

Melting point:
41-43 °C(lit.)
Boiling point:
398.71°C (rough estimate)
Density 
1.208 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.506(lit.)
Flash point:
>230 °F
storage temp. 
-20°C
solubility 
Dichloromethane; Chloroform; Ethyl Acetate; Methanol; DMF;
form 
Oil
color 
Pale Brown
optical activity
[α]/D 7.0±0.5°, neat
BRN 
89800
InChIKey
SRKDUHUULIWXFT-LLVKDONJSA-N
CAS DataBase Reference
23788-74-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-37/39
WGK Germany 
3
10-21
HS Code 
29329900

MSDS

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(R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE Usage And Synthesis

Chemical Properties

clear yellow to light brown viscous liquid

Uses

(R)-(-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate is a chiral building block. It is used to prepare the antifungal agent ketoconazole. It is also used to prepare acyclic Nucleotide Analogs Derived from 8-Azapurines with antiviral activities.

(R)-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATESupplier

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