Basic information Uses Safety Supplier Related
ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  aliphatic ketones >  (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol

Basic information Uses Safety Supplier Related

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol Basic information

Product Name:
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
Synonyms:
  • L-ALPHA,BETA-ISOPROPYLIDENEGLYCEROL
  • L-2,3-O-ISOPROPYLIDENE-SN-GLYCEROL
  • L-(-)-1,2-ISOPROPYLIDENEGLYCEROL
  • 2,3-ISOPROPYLIDENE-SN-GLYCEROL
  • 2,3-O-ISOPROPYLIDENE-L-GLYCEROL
  • (-)-2,3-O-ISOPROPYLIDENE-SN-GLYCEROL
  • R-GLYCEROL ACETONIDE
  • R-(-)-2,3-O-ISOPROPYLIDENEGLYCEROL
CAS:
14347-78-5
MF:
C6H12O3
MW:
132.16
EINECS:
604-360-5
Product Categories:
  • Chiral Reagents
  • Heterocycles
  • Chiral Building Blocks
  • Dioxanes & Dioxolanes
  • Synthetic Organic Chemistry
  • Inhibitors
  • pharmacetical
  • Dioxolanes
  • Glycidyl Compounds, etc. (Chiral)
Mol File:
14347-78-5.mol
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(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol Chemical Properties

alpha 
-13.7 º (neat)
Boiling point:
72-73 °C/8 mmHg (lit.)
Density 
1.062 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.434
Flash point:
176 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
14.20±0.10(Predicted)
form 
Liquid
Specific Gravity
1.062
color 
Clear colorless to light yellow
optical activity
[α]20/D 13.7°, neat
Water Solubility 
miscible
Merck 
14,5213
BRN 
80117
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
RNVYQYLELCKWAN-RXMQYKEDSA-N
CAS DataBase Reference
14347-78-5(CAS DataBase Reference)
NIST Chemistry Reference
D-Acetone glycerol(14347-78-5)
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Safety Information

Safety Statements 
23-24/25
WGK Germany 
3
RTECS 
JI0400000
10
HS Code 
29329990

MSDS

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(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol Usage And Synthesis

Uses

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol is a MEK inhibitor with antitumor activity.

Chemical Properties

colourless liquid

Uses

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol may be used to prepare:

  • (R)-2,2-Dimethyl-4-benzoxymethyl-1,3-dioxolane.
  • ((S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate)-1,3-dioxolane.
  • (S)-Glyceraldehyde acetonide.
  • Tetraoxaspiroundecanes, diglycerides, glyceryl phosphates, and spiropyrans.

Uses

A MEK inhibitor

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanolSupplier

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