(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Chemical Properties

Melting point:

29-31 °C

alpha 

4.2 º (c=10, abs.alcohol)

Boiling point:

398.71°C (rough estimate)

Density 

1.208 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.506(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,2-8°C

form 

powder to lump to clear liquid

color 

White or Colorless to Light yellow

optical activity

[α]26/D +7.5°, c = 2% in DMF

BRN 

89799

CAS DataBase Reference

23735-43-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

F 

10-21

HS Code 

29329990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has been used as a reactant for the synthesis of 16-(3-trifluoromethyl)phenoxy PGF2α analog travoprost (T715600) which has potent topical ocular activity. (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has also been used for the preparation of p38 mitogen activated protein (MAP) kinase inhibitors.

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate(23735-43-5)Related Product Information

• ETHANE
• Dimethyl sulfoxide
• Methanol
• Xylene
• Dimethyl sulfate
• Dimethyl phthalate
• Sulfanilic acid
• N,N-Dimethylformamide
• Calcium dobesilate
• Amlodipine Besylate
• p-Toluenesulfonic acid
• Dimethyl ether
• Dodecylbenzenesulphonic acid
• Benzenesulfonic acid
• Linear alkyl benzenesulphonate
• Dimethyl carbonate
• Dimethyl fumarate
• Dacthal