4-Hydroxy-2-methylquinoline Chemical Properties

Melting point:

234-236 °C(lit.)

Boiling point:

284.68°C (rough estimate)

Density 

1.1202 (rough estimate)

refractive index 

1.6070 (estimate)

storage temp. 

Sealed in dry,Room Temperature

form 

powder to crystal

pka

4.44±0.40(Predicted)

color 

White to Light yellow

Water Solubility 

Slightly soluble in water.

λmax

317nm(CHCl3)(lit.)

BRN 

118320

LogP

1.902 (est)

CAS DataBase Reference

607-67-0(CAS DataBase Reference)

NIST Chemistry Reference

4-Quinolinol, 2-methyl-(607-67-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39-36/37/39-22

WGK Germany 

3

HS Code 

29334900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Hydroxy-2-methylquinoline Usage And Synthesis

Chemical Properties

BEIGE POWDER

Uses

4-Hydroxy-2-methylquinoline is act as an intermediate in the synthesis of dequalinium chloride and as pharmaceutical intermediate.

Uses

4-Hydroxy-2-methylquinoline can be used as an intermediate in the synthesis of a wide range of medicinally important compounds such as:

• Synthesis of 2-(quinolin-4-yloxy)acetamides as potent antitubercular agents.
• Synthesis of 2-arylethenylquinoline derivatives for the treatment of Alzheimer′s disease.
• Synthesis of 1,10-diethoxy-1H-pyrano[4,3-b]quinolones as antibacterial agents.
• Synthesis of phenylimidazole-pyrazolo[1,5-c]quinazolines as potent phophodiesterase 10A (PDE10A) inhibitors.

Definition

ChEBI: 2-Methyl-4-quinolinol is a member of quinolines.

4-Hydroxy-2-methylquinoline(607-67-0)Related Product Information

• Isoquinoline
• 6-Hydroxy-2(1H)-3,4-dihydroquinolinone
• QUINOLINE SULPHATE
• 8-Hydroxyquinoline
• Quinaldine
• Bensulfuron methyl
• Ethoxyquin
• Quinhydrone
• Methyl acrylate
• CHLOROPHOSPHONAZO III
• Thiophanate-methyl
• 4-Cyanophenol
• Kresoxim-methyl
• Methylparaben
• 4-methylquinoline
• Quinclorac
• Methyl acetate
• METHYL THIOPHENE-2-CARBOXYLATE